Study Summary
This trial found that acute use of electronic cigarettes increased oxidative stress and inflammation.
- Electronic Cigarette Use, Oxidative Stress, Inflammation
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 1 Secondary · Reporting Duration: within 4 hours of e-cig use
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
2 Treatment Groups
E-cig
1 of 2
sham
1 of 2
Experimental Treatment
120 Total Participants · 2 Treatment Groups
Primary Treatment: e-cigarette · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 21 - 45 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Kelesidis, Theodoros, Elizabeth Tran, Sara Arastoo, Karishma Lakhani, Rachel Heymans, Jeffrey Gornbein, and Holly R. Middlekauff. 2020. “Elevated Cellular Oxidative Stress in Circulating Immune Cells in Otherwise Healthy Young People Who Use Electronic Cigarettes in a Cross‐sectional Single‐center Study: Implications for Future Cardiovascular Risk”. Journal of the American Heart Association. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/jaha.120.016983.
- Holly R Middlekauff 2019. "ECigs, Inflammation and Oxidative Stress". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03823885.
Frequently Asked Questions
Is this experiment actively searching for new volunteers?
"Affirmative. Data hosted on clinicaltrials.gov suggests that the research project, which was initially posted on February 8th 2019, is currently enrolling patients. An approximate 120 participants need to be admitted from 1 medical centre." - Anonymous Online Contributor
How many individuals can participate in this research?
"Affirmative, according to clinicaltrials.gov, the medical trial is still open for enrolment. The study was initially posted on February 8th 2019 and last updated September 6th 2022; with a target of 120 participants across 1 site." - Anonymous Online Contributor
Who meets the criteria to partake in this trial?
"Eligibility for this scientific study requires inflammation and a patient age between 21 and 45. A total of 120 individuals are anticipated to enroll in the trial." - Anonymous Online Contributor
Does this investigation have an upper age limit for participants?
"This research project adheres to age restrictions, as the minimum enrollment age is 21 and the maximum permissible age is 45." - Anonymous Online Contributor