← Back to Search

Telemedicine-Coordinated Medication Care for Elderly Patient Transitions (IMPROVE-IT Trial)

N/A

Recruiting

Led By Anne Holbrook

Research Sponsored by St. Joseph's Healthcare Hamilton

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Adults over the age of 65 years.

Admitted to Medicine or Surgery services for more than 2 days.

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through the study completion, an average of 2 years

Awards & highlights

IMPROVE-IT Trial Summary

This trial tests whether a Clinical Pharmacology team can help reduce medication-related harm & improve care coordination for older Canadians in hospital and at home using telemedicine.

Who is the study for?

This trial is for Canadian seniors over 65 who've been hospitalized for more than 2 days, have had another hospital stay in the past year, and are on five or more long-term medications including one that's known to be risky. They must understand and agree to participate.Check my eligibility

What is being tested?

The study tests if a Clinical Pharmacology specialist team can improve medication safety for older patients by stopping unneeded drugs, adjusting doses, or switching to safer options using telemedicine from hospital to home.See study design

What are the potential side effects?

Since this trial focuses on improving medication prescribing practices rather than testing new drugs, side effects may include withdrawal symptoms from stopping certain medications or adjustments as the specialists optimize each patient's regimen.

IMPROVE-IT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am over 65 years old.

Select...

I have been in the hospital under Medicine or Surgery for over 2 days.

Select...

I am on 5 or more long-term medications, including a TRIIM-Med.

IMPROVE-IT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through the study completion, an average of 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through the study completion, an average of 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and through the study completion, an average of 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Clinical Outcome: The number of TRIIM-Meds successfully deprescribed.

Feasibility Outcome: Recruitment rate for eligible patients.

Secondary outcome measures

Feasibility Outcomes of CPT consultation volume capacity and potential to apply the intervention entirely through telemedicine.

Feasibility Outcomes of likelihood of the intervention proving cost-effective.

Feasibility Outcomes of patient retention rate.

+2 more

IMPROVE-IT Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intervention ArmExperimental Treatment1 Intervention

Clinical Pharmacology specialist team approach starting in hospital and following up with the patient at home using telemedicine and detailed communication with them, their caregiver, family physician, community pharmacist and other specialists.

Group II: Control Arm (Usual care)Active Control1 Intervention

Patients will receive a best possible medication history (BPMH) as do the intervention patients, then usual care by their primary team.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

St. Joseph's Healthcare HamiltonLead Sponsor

196 Previous Clinical Trials

25,244 Total Patients Enrolled

Canadian Institutes of Health Research (CIHR)OTHER_GOV

1,345 Previous Clinical Trials

26,453,214 Total Patients Enrolled

15 Trials studying Aging

4,592 Patients Enrolled for Aging

Anne HolbrookPrincipal InvestigatorSJHH

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the scope of the population under evaluation for this research?

"Affirmative. Data hosted on clinicaltrials.gov indicates that this medical trial, initially posted on June 1st 2023, is actively seeking participants. 300 individuals are being sought at a single healthcare facility."

Answered by AI

Are there any vacancies still available for participants in this trial?

"Currently, clinicaltrials.gov reports that this trial is actively seeking candidates to participate. This research was initially posted on June 1st 2023 and has been updated as of November 20th 2023."

Answered by AI

What are the expected results of this medical study?

"This clinical trial, which will be monitored for a period of two years on average, seeks to measure the number of TRIIM-Meds successfully deprescribed. Secondary metrics include patient-important outcomes such as health related quality of life (using EQ-5D-5L), feasibility outcomes regarding patient retention rate and cost effectiveness. Healthcare resource utilization questionnaires are used to assess these last two criteria given the intervention's potential impact in lowering healthcare costs compared to control groups."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Improving Medication Prescribing-Related Outcomes for Vulnerable Elderly In Transitions

Dr. Anne Holbrook 2023. "Improving Medication Prescribing-Related Outcomes for Vulnerable Elderly In Transitions". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04077281.