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Exercise and sensory stimulation for Swallowing Disorders (PRESIDE Trial)

N/A
Waitlist Available
Led By Dale M Needham, MD PhD
Research Sponsored by Johns Hopkins University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up participants will be evaluated an expected average of 48 hours after extubation
Awards & highlights

PRESIDE Trial Summary

This trial will investigate whether early intervention for swallowing disorders during endotracheal intubation can improve patient outcomes.

Eligible Conditions
  • Swallowing Disorders
  • Mechanical Ventilation Complication
  • Ventilator-Associated Complication

PRESIDE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~participants will be evaluated an expected average of 48 hours after extubation
This trial's timeline: 3 weeks for screening, Varies for treatment, and participants will be evaluated an expected average of 48 hours after extubation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of participants aspirating during fiberoptic endoscopic swallow study

PRESIDE Trial Design

1Treatment groups
Experimental Treatment
Group I: Exercise and sensory stimulationExperimental Treatment1 Intervention
60-minute sessions with sensory electrical stimulation (SES) applied 5 days per week with oromotor exercises completed when patient is able to participate

Find a Location

Who is running the clinical trial?

Johns Hopkins UniversityLead Sponsor
2,260 Previous Clinical Trials
14,820,722 Total Patients Enrolled
National Institute on Deafness and Other Communication Disorders (NIDCD)NIH
328 Previous Clinical Trials
178,238 Total Patients Enrolled
Dale M Needham, MD PhDPrincipal InvestigatorJohns Hopkins University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
ChestJournal
Laryngeal Complications of Prolonged Intubation
Colice, Gene L., Therese A. Stukel, and Bradley Dain. 1989. “Laryngeal Complications of Prolonged Intubation”. Chest. Elsevier BV. doi:10.1378/chest.96.4.877.
Critical Care MedicineJournal
Postextubation Fiberoptic Endoscopic Evaluation of Swallowing After Prolonged Endotracheal Intubation: A Randomized, Prospective Trial
Barquist, Erik, Margaret Brown, Stephen Cohn, Donna Lundy, and Julie Jackowski. 2001. “Postextubation Fiberoptic Endoscopic Evaluation of Swallowing After Prolonged Endotracheal Intubation: A Randomized, Prospective Trial”. Critical Care Medicine. Ovid Technologies (Wolters Kluwer Health). doi:10.1097/00003246-200109000-00009.
American Journal of Respiratory and Critical Care MedicineJournal
Rapidly Progressive Diaphragmatic Weakness and Injury During Mechanical Ventilation in Humans
Jaber, Samir, Basil J. Petrof, Boris Jung, Gérald Chanques, Jean-Philippe Berthet, Christophe Rabuel, Hassan Bouyabrine, et al.. 2011. “Rapidly Progressive Diaphragmatic Weakness and Injury During Mechanical Ventilation in Humans”. American Journal of Respiratory and Critical Care Medicine. American Thoracic Society. doi:10.1164/rccm.201004-0670oc.
ChestJournal
Icu-acquired Weakness
Schweickert, William D., and Jesse Hall. 2007. “Icu-acquired Weakness”. Chest. Elsevier BV. doi:10.1378/chest.06-2065.
~6 spots leftby Apr 2025
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