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Personalized Treatment Approaches for Anxiety and Traumatic Stress Disorders

University of Kentucky, Lexington, KY
Targeting 3 different conditionsStandard UP Treatment +2 moreN/AWaitlist AvailableLed by Shannon Sauer-ZavalaResearch Sponsored by Shannon E. Sauer-Zavala

Study Summary

This trial will test if a new way of delivering treatment to people with anxiety disorders is feasible, tolerable, and acceptable. It will also test if this new way is more efficient than the standard way of delivering treatment.

Eligible Conditions
  • Obsessive-Compulsive Disorder
  • Anxiety Disorders
  • Post-Traumatic Stress Disorder

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
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Your current medication regimen must be steady and unchanged during the study.
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You have been diagnosed with anxiety disorder, trauma- or stressor-related disorder, or obsessive-compulsive disorder.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks (baseline, week 1, week, 2, week, 3.....week 12)
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks (baseline, week 1, week, 2, week, 3.....week 12) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Clinical Severity
Change in Clinician-Rated Anxiety Symptoms
Change in Clinician-Rated Depressive Symptoms
+3 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

6Treatment groups
Experimental Treatment
Group I: Standard Group, Full InterventionExperimental Treatment1 Intervention
Participants in this group will receive 12 sessions of treatment in accordance with the standard, published Unified Protocol (UP) manual.
Group II: Standard Group, Brief InterventionExperimental Treatment1 Intervention
Participants in this group will receive 6 sessions of treatment in accordance with the standard, published Unified Protocol (UP) manual.
Group III: Compensation Group, Full InterventionExperimental Treatment1 Intervention
Participants in this group will receive 12 sessions of treatment organized to prioritize skills that compensate for patient weaknesses.
Group IV: Compensation Group, Brief InterventionExperimental Treatment1 Intervention
Participants in this group will receive 6 sessions of treatment organized to prioritize skills that compensate for patient weaknesses.
Group V: Capitalization Group, Full InterventionExperimental Treatment1 Intervention
Participants in this group will receive 12 sessions of treatment organized to prioritize skills that capitalize on patient strengths.
Group VI: Capitalization Group, Brief InterventionExperimental Treatment1 Intervention
Participants in this group will receive 6 sessions of treatment organized to prioritize skills that capitalize on patient strengths.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Capitalization UP Treatment
2019
N/A
~80
Standard UP Treatment
2019
N/A
~80
Compensation UP Treatment
2019
N/A
~80

Find a Location

Who is running the clinical trial?

Shannon E. Sauer-ZavalaLead Sponsor
4 Previous Clinical Trials
270 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
72 Patients Enrolled for Obsessive-Compulsive Disorder
National Institute of Mental Health (NIMH)NIH
2,716 Previous Clinical Trials
2,423,314 Total Patients Enrolled
65 Trials studying Obsessive-Compulsive Disorder
13,915 Patients Enrolled for Obsessive-Compulsive Disorder
Shannon Sauer-ZavalaPrincipal InvestigatorUniversity of Kentucky
2 Previous Clinical Trials
112 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
72 Patients Enrolled for Obsessive-Compulsive Disorder

Media Library

Capitalization UP Treatment Clinical Trial Eligibility Overview. Trial Name: NCT04642898 — N/A
Obsessive-Compulsive Disorder Research Study Groups: Capitalization Group, Full Intervention, Compensation Group, Full Intervention, Standard Group, Brief Intervention, Capitalization Group, Brief Intervention, Compensation Group, Brief Intervention, Standard Group, Full Intervention
Obsessive-Compulsive Disorder Clinical Trial 2023: Capitalization UP Treatment Highlights & Side Effects. Trial Name: NCT04642898 — N/A
Capitalization UP Treatment 2023 Treatment Timeline for Medical Study. Trial Name: NCT04642898 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still openings for volunteers in this trial?

"Correct. According to information located on clinicaltrials.gov, this medical trial is presently recruiting patients and was first advertised in June of 2021. As it stands, 66 participants are required from a single site with the latest update occurring September 26th 2022."

Answered by AI

What is the current population of subjects participating in this research?

"Affirmative. Clinicaltrials.gov hosts information that confirms this medical trial is recruiting participants; it was first announced on June 22nd 2021 and subsequently updated on September 26th 2022. 66 patients need to be enrolled from 1 particular location for the study to continue."

Answered by AI

Who else is applying?

What state do they live in?
Ohio
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
What site did they apply to?
University of Kentucky
Recent research and studies
clinicaltrials.govStudy
Increasing Treatment Efficacy Using SMART Methods for Personalizing Care
Shannon E. Sauer-Zavala 2021. "Increasing Treatment Efficacy Using SMART Methods for Personalizing Care". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04642898.
All > Ocd Cincinnati > Ocd
~8 spots leftby Apr 2024
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