← Back to Search

Online Cough Suppression Therapy for Chronic Cough

N/A

Recruiting

Led By Jane Reynolds, PhD

Research Sponsored by University of Montana

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Suffering from a cough lasting at least eight weeks that is largely unproductive (cough up no more than a few teaspoons worth of clear or white sputum or mucus in a 24-hour period)

Self-report of receiving the following assessments for current cough symptoms with unremarkable results: physical evaluation by at least one physician, chest x-ray

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, pre-intervention, and immediately after the intervention

Awards & highlights

Study Summary

This trial assesses an online treatment to help people with chronic cough that doesn't respond to traditional treatments. Participants will use online treatments and apps to monitor their cough.

Who is the study for?

This trial is for people in Montana with a chronic cough lasting at least eight weeks, triggered by stimuli like cold air or strong smells. Participants must be able to use a computer or smartphone, have internet access, and not be current smokers. They should have had unremarkable physical evaluations and chest x-rays, and cannot be on certain medications like ACE inhibitors or neuromodulators.Check my eligibility

What is being tested?

The study tests an Internet-based behavioral therapy (iBCST) against a sham treatment to see if it helps suppress chronic coughs. It's randomized and placebo-controlled; participants will also use the Hyfe app to monitor their cough frequency and some will participate in interviews.See study design

What are the potential side effects?

Since this is a behavioral intervention using internet resources rather than medication, there are no direct side effects as one would expect from drugs. However, participants may experience frustration or lack of improvement if the therapy proves ineffective.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have had a dry cough for over eight weeks.

Select...

I've had a doctor check and an x-ray for my cough, both were normal.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, pre-intervention, and immediately after the intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, pre-intervention, and immediately after the intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, pre-intervention, and immediately after the intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Cough-Related Quality of Life

Secondary outcome measures

Hourly Cough Rate

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Internet-Behavioral Cough Suppression TherapyExperimental Treatment1 Intervention

Participants will watch treatment-specific educational and training videos and perform the training exercises as recommended. There are a total of five videos ranging from 2-5 minutes in length. Participants will be asked to watch the videos at least once weekly. Daily training exercises will be discussed in the videos and should take no more than a few minutes to complete every day. All exercises are non-invasive and are not physically demanding. Each week participants will complete a progress check question that will take less than one minute to answer, indicating whether they are watching the videos and completing the exercises as recommended.

Group II: Sham TreatmentPlacebo Group1 Intervention

Participants will watch sham treatment-specific educational and training videos and perform the training exercises as recommended. There are a total of five videos ranging from 2-5 minutes in length. Participants will be asked to watch the videos at least once weekly. Daily training exercises will be discussed in the videos and should take no more than a few minutes to complete every day. All exercises are non-invasive and are not physically demanding. Each week participants will complete a progress check question that will take less than one minute to answer, indicating whether they are watching the videos and completing the exercises as recommended.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of MontanaLead Sponsor

24 Previous Clinical Trials

3,526 Total Patients Enrolled

2 Trials studying Cough

41 Patients Enrolled for Cough

Jane Reynolds, PhDPrincipal InvestigatorAssistant Professor

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it currently possible for individuals to enroll in this clinical experiment?

"The clinicaltrial.gov website reveals that this trial is actively recruiting patients, having been posted on July 1st 2023 and updated most recently on October 12th 2023."

Answered by AI

What is the maximum capacity for participants in this clinical trial?

"Affirmative. According to clinicaltrials.gov, this medical study has been recruiting since July 1st 2023 and is still searching for participants as of October 12th 2023. 48 volunteers are required from a single site location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Internet-Behavioral Cough Suppression Therapy

2023. "Internet-Behavioral Cough Suppression Therapy". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05770401.