← Back to Search

MRI for Colorectal Cancer

N/A
Waitlist Available
Led By Priya Bhosale
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, an average of a year.
Awards & highlights

Study Summary

This trial is testing a new MRI technique to see if it can better detect liver damage caused by chemotherapy in patients with colorectal cancer that has spread to the liver.

Eligible Conditions
  • Colorectal Cancer Metastatic to the Liver

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, an average of a year.
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of a year. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Magnetic Resonance Displacement Encoding with Stimulated Echo (MR DENSE) imaging data of patients treated with chemotherapy prior to resection of metastases to explore its utility in detecting sinusoidal liver injury.

Side effects data

From 2022 Phase 3 trial • 53 Patients • NCT00033293
19%
87900-Vomiting(targeted toxicity)
15%
11400-Agitation
8%
11600-Alanine aminotransferase increased
8%
16800-Bladder infection
8%
44800-Infections and infestations - Other specify
8%
58700-Nystagmus
4%
15000-Aspartate aminotransferase increased
4%
88500-White blood cell decreased
4%
15300-Ataxia
4%
33900-Fever
4%
25700-Diarrhea
4%
43100-Hypokalemia
4%
69700-Rash maculo-papular(targeted toxicity)
4%
13200-Anemia
4%
33300-Febrile neutropenia
4%
57600-Nausea(targeted toxicity)
4%
20500-Catheter related infection
4%
58300-Neutrophil count decreased
4%
41300-Hypercalcemia
4%
41400-Hyperglycemia(targeted toxicity)
4%
41600-Hyperkalemia
4%
42600-Hypoalbuminemia
4%
42700-Hypocalcemia
4%
64400-Personality change
4%
41500-Hyperhidrosis
4%
13500-Anorexia
100%
80%
60%
40%
20%
0%
Study treatment Arm
Arm I (Chemotherapy, Immunoglobulin Therapy)
Arm II (Chemotherapy, Observation)

Trial Design

1Treatment groups
Experimental Treatment
Group I: Diagnostic (standard of care MRI, MR DENSE MRI)Experimental Treatment1 Intervention
Patients undergo standard of care MRI and then undergo an MRI of the liver using MR DENSE imaging sequences over 60-90 minutes. Healthy volunteers undergo MRI of the liver using DENSE imaging sequences.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Magnetic Resonance Imaging
2017
Completed Phase 3
~1190

Find a Location

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,970 Previous Clinical Trials
1,787,097 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,658 Previous Clinical Trials
40,924,641 Total Patients Enrolled
Priya BhosalePrincipal InvestigatorM.D. Anderson Cancer Center
1 Previous Clinical Trials
50 Total Patients Enrolled

Media Library

Magnetic Resonance Imaging Clinical Trial Eligibility Overview. Trial Name: NCT05059717 — N/A
Colorectal Cancer Research Study Groups: Diagnostic (standard of care MRI, MR DENSE MRI)
Colorectal Cancer Clinical Trial 2023: Magnetic Resonance Imaging Highlights & Side Effects. Trial Name: NCT05059717 — N/A
Magnetic Resonance Imaging 2023 Treatment Timeline for Medical Study. Trial Name: NCT05059717 — N/A
Colorectal Cancer Patient Testimony for trial: Trial Name: NCT05059717 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any spots open to join this research project?

"As indicated on the clinicaltrials.gov database, this trial is no longer accepting applicants at present. This particular study was first posted in July 2018 and most recently updated November 2021; however, there are currently 860 other trials that are open to new participants."

Answered by AI

Who else is applying?

What state do they live in?
Texas
What site did they apply to?
M D Anderson Cancer Center
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0

Why did patients apply to this trial?

I will try anything to get myself and others healthy. I unexpectedly discovered I had colon cancer a year ago during routine colonoscopy. I had surgery and chemo and was successfully treated. Just found out after a year it has not returned according to CT scans.
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
An Investigational Scan (MR DENSE) in Detecting Early Chemotherapy-Related Liver Injury Before Surgery in Patients With Resectable Colorectal Liver Metastases
2018. "An Investigational Scan (MR DENSE) in Detecting Early Chemotherapy-Related Liver Injury Before Surgery in Patients With Resectable Colorectal Liver Metastases". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05059717.
~0 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top