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Study Summary
This trial is testing the accuracy of a new, rapid MRI approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS). The new imaging approach can create multiple types of MR images in about 5 minutes, without contrast administration (and sedation even in young children). The investigators will also study how advanced MRI, including susceptibility-weighted and diffusion tensor imaging can detect detailed signs of brain vascular and neuronal reorganization that helps improve neurological and cognitive outcome of children and young adults with SWS.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I am between 3 and 30 years old and healthy.You have a specific type of birthmark on your face, or evidence of a related brain condition.My child, who is 3 or older, speaks English well.I have no history of mental health or neurological conditions.I am not currently pregnant.I do not have kidney disease that would make MRI contrast unsafe.I am between 3 months and 30 years old.I am between 3 and 30 years old.You have metal in your head or mouth that would make it unsafe to have an MRI scan, or you have any other metal or electronic device that should not be used during an MRI scan.I am between 3 months and 30 years old with Sturge-Weber syndrome.You have a history of feeling very scared in small, enclosed spaces and can't stay still in a scanner for up to 30 minutes.
- Group 1: Patients with SWS or high-risk facial port-wine birthmark
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To whom is participation in this clinical experiment open?
"To enroll in this particular trial, 80 individuals with sturge-weber syndrome must be found within the specified age range of 3 months to 30 years. Additionally, these participants ought not have a history of neurological or psychiatric illness."
Are individuals aged 50 or above accepted into this medical experiment?
"This clinical study is seeking participants between the ages of 3 months and 30 years old. The research database shows 377 studies for minors and 996 studies related to adults over 65."
Is recruitment for this trial still open?
"Affirmative. According to data hosted on clinicaltrials.gov, this medical trial is actively recruiting subjects as of January 5th 2022. It was initially posted on March 1st 2020 and requires 80 participants from a single site."
How many participants are being tracked in this scientific investigation?
"Affirmative. Evidence hosted on clinicaltrials.gov indicates that this medical trial, which was initially posted in March of 2020, is actively seeking participants. Eighty people need to be recruited from one location for the study's completion."
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