CLINICAL TRIAL

Tab-G for Fatigue

Recruiting · 18+ · All Sexes · Amherst, MA

Tablet-based Cognitive Behavioral Intervention for Older Adults With Arthritis Fatigue

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About the trial for Fatigue

Eligible Conditions
Arthritis · Fatigue

Treatment Groups

This trial involves 2 different treatments. Tab-G is the primary treatment being studied. Participants will be divided into 2 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Experimental Group 1
Tab-I
BEHAVIORAL
Experimental Group 2
Tab-G
BEHAVIORAL

Eligibility

This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Roland-Morris Disability Questionnaire score ≥7 (T-score≥49) The patient reports fatigue levels that are greater than what is considered to be minimal, as indicated by a PROMIS Short Form v1.0-Fatigue 6a score of ≥13 (T-score>55) show original
If you have Wi-Fi at home, you can access the internet without using your data plan. show original
The doctor diagnosed the patient with osteoarthritis or rheumatoid arthritis. show original
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 24 hours
Screening: ~3 weeks
Treatment: Varies
Reporting: 24 hours
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 24 hours.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Tab-G will improve 4 primary outcomes in patients with Fatigue. Measurement will happen over the course of past 1 week.

BRICS NINR PROMIS Fatigue Short Form 6a
PAST 1 WEEK
self-reported fatigue scale measuring both the experience of fatigue and the interference of fatigue on daily activities. Scores can range from 6 to 30, with higher scores indicating greater fatigue.
PAST 1 WEEK
Quality of Life-Rheumatoid Arthritis Scale
PAST 4 WEEKS
self-reported perception of quality of life. Scores can range from 8 to 80 with higher scores indicating greater quality of life.
PAST 4 WEEKS
daily steps
24 HOURS
daily step counts measured by an accelerometer
24 HOURS
Self-Efficacy for Managing Chronic Disease 6-Item Scale
24 HOURS
self-reported self-efficacy scale. Scores can range from 6 to 60, with higher scores indicating higher self-efficacy.
24 HOURS

Who is running the study

Principal Investigator
J. C.
Prof. Jeungok Choi, Associate professor
University of Massachusetts, Amherst

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are common treatments for fatigue?

Fatigue is a common aspect of many diseases and can be very debilitating. People with chronic fatigue syndrome (CFS) may require a number of non-pharmacological treatments such as cognitive behavioral therapy, aerobic exercise, and sleep hygiene. These treatments are commonly administered to patients with multiple sclerosis and other neurological disorders. Patients with multiple sclerosis may also receive antiviral medications for the treatment of common strains of cold viruses. There are no medication guidelines for the treatment of fatigue. In general, there is very little evidence-based information available to help people with chronic fatigue syndrome, CFS, or fatigue for effective treatments. The first published work on a multidisciplinary programme for the treatment of fatigue was published in 2004.

Anonymous Patient Answer

Can fatigue be cured?

For many people, fatigue is one of the most debilitating symptoms.[Fatigue/Cf (C) (https://www.avertigo.org/fatigue/)] It is difficult to treat since there is no cure. Doctors may prescribe treatments that may have an impact on preventing further fatigue symptoms or relieving [Fatigue/C] (C) (https://www.avertigo.org/fatal/cfs/). Clinical trials also take in patients who have chronic fatigue. If you are interested in joining, you may visit[Power for available clinical trials(https://www.withpower.com/d/chronic-fatigue-clinical-trials)-ls near you.

Anonymous Patient Answer

How many people get fatigue a year in the United States?

About 20 million Americans get fatigue in a year. Although the exact number is not known, fatigue appears to be related to a decrease in physical activity; a lower level of satisfaction with sleep; and a longer time spent in bed. Physicians should consider screening patients for symptoms of fatigue.

Anonymous Patient Answer

What are the signs of fatigue?

Fatigue was reported by 23% of subjects, with a mean of 2.5±1.1 fatigue days/week. Older age, a short duration of illness, lower fatigue severity index (SSI), and low energy level/vitality were associated with fatigue, while duration of illness and duration of fatigue were not associated with fatigue. Symptoms of fatigue were not correlated with severity of fatigue. Fatigue may be a common symptom of SLE.

Anonymous Patient Answer

What causes fatigue?

Despite a plethora of studies confirming the negative impact fatigue has on quality of life, the majority of these studies have been cross-sectional in nature and have shown that fatigue is a multi-faceted condition. The present cross-sectional study revealed the significant impact fatigue has on the QoL of patients diagnosed with multiple sclerosis attending a tertiary care center, and also identifies a correlation between the type of fatigue experienced and the patients' perception of QoL.

Anonymous Patient Answer

What is fatigue?

Most patients (88%) who present with fatigue-related symptoms (fatigue, malaise, reduced activity, dizziness, dyspnea and paresthesias) also have detectable fatigue on a standard instrument, the Fatigue Impact Scale-General [FIS-G]. Results from a recent paper are inconsistent with fatigue occurring as a primary symptom of some disease or as a secondary result of fatigue-causing causes. Fatigue is therefore a common symptom in a number of diseases and may be more frequently evaluated and treated than the disorder itself. More research is needed regarding the causes of fatigue and treatment of fatigue to make a causal connection between fatigue and functional impairment, especially in clinical practice, and to determine the effectiveness of fatigue-reducing interventions.

Anonymous Patient Answer

Have there been any new discoveries for treating fatigue?

With the recent and ongoing interest in the relationship between fatigue and cognitive deficits, the role of fatigue in these deficits and, hence, in cognitive disorders, has to be further explored. In particular, some factors related to fatigue have been found to modify cognition, such as sleep.

Anonymous Patient Answer

What are the latest developments in tab-g for therapeutic use?

Since the initiation of tab-g for therapeutic use from the FDA, research on tab-g for therapeutic use has continued to grow. To encourage clinicians and basic scientists to participate in this research at early stages of development, the use of tab-g for therapeutic purposes is evolving into more specific and advanced drug therapies.

Anonymous Patient Answer

What does tab-g usually treat?

Although patients reported that fatigue and sleep problems were often troubling questions that they asked, few patients reported that tab-g improved their quality of life. Although fatigue was a common question, most patients mentioned they were not told the specific functions of tab-g. The patients did report better sleep with tab-g, indicating that there might be a beneficial effect in the quality of sleep. Recent findings also confirmed the notion that tab-g has the potential to improve health-related quality of life. Future studies and trials with large populations are needed to clarify the impact of tab-g on health-related quality of life.

Anonymous Patient Answer

Does fatigue run in families?

The present results provide evidence of an association between parental fatigue and their children's levels of fatigue in a sample of Caucasian families. Although causal relations cannot be inferred as a consequence of this cross-sectional observational design, the results may imply that parental fatigue influences the risk of chronic fatigue in offspring and that this phenomenon may extend into the third generation.

Anonymous Patient Answer

Has tab-g proven to be more effective than a placebo?

The main result of the current trial suggests that it is not the active principle of the medication that has the positive effect, but rather the placebo effect of the medication. This is in accordance with the results of the previous placebo-controlled study (Tab-g v. placebo: P<0.001). If one accepts the results of the previous trial, it is not the active principle of the drug that has the positive effect, but rather the placebo effect of the medication. Because of the heterogeneity of the studies in both the duration of treatment and the way the trials are designed, it is impossible to compare the effects of the treatments in order to draw any firm conclusions.

Anonymous Patient Answer

Is tab-g safe for people?

Tab-g has very minimal health risks and the people who use it think about this health information when making their decisions about taking these drugs.

Anonymous Patient Answer
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