LTGO-Home Based Exercise for Transplantation, Lung

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Transplantation, Lung+1 More
LTGO-Home Based Exercise - Behavioral
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing a behavioral exercise intervention to help lung transplant recipients learn and practice exercises to improve their condition and adopt an active lifestyle.

Eligible Conditions
  • Transplantation, Lung
  • Exercise

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

11 Primary · 2 Secondary · Reporting Duration: The change will be measured at baseline to 6 months, post-randomization.

Month 6
Physical function- Lower Body Strength-Change is being Assessed from baseline to 6 months.
Month 3
Blood Pressure Control-Change Assessed, from baseline to 3 months
Physical Activity-Change is being Assessed from baseline to 3 months.
Physical function- Balance-Change is being Assessed from baseline to 3 months
Physical function- Lower Body Strength-Change is being Assessed from baseline to 3 months.
Physical function- Maximal exercise watts per Kg of bodyweight change is being assess from baseline to 3 months.
Physical function- respiratory related quality of life is being assess from baseline to 3 months.
Physical function-Walking, Change is being Assessed from baseline to 3 months
Month 6
Blood Pressure Control-Change Assessed, from baseline to 6 months
Physical Activity-Change is being Assessed from baseline to 6 months.
Physical function- Balance-Change is being Assessed from baseline to 6 months
Physical function- Walking-Change is being Assessed from baseline to 6months
Physical function- respiratory related quality of life is being assess from baseline to 6 months.

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Enhanced Usual Care
1 of 2
LTGO-Home Based Exercise
1 of 2
Active Control
Experimental Treatment

112 Total Participants · 2 Treatment Groups

Primary Treatment: LTGO-Home Based Exercise · No Placebo Group · N/A

LTGO-Home Based Exercise
Behavioral
Experimental Group · 1 Intervention: LTGO-Home Based Exercise · Intervention Types: Behavioral
Enhanced Usual Care
Behavioral
ActiveComparator Group · 1 Intervention: Enhanced Usual Care · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: the change will be measured at baseline to 6 months, post-randomization.

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,600 Previous Clinical Trials
6,285,603 Total Patients Enrolled
5 Trials studying Transplantation, Lung
2,408 Patients Enrolled for Transplantation, Lung
National Institute of Nursing Research (NINR)NIH
521 Previous Clinical Trials
286,071 Total Patients Enrolled
Annette DeVito Dabbs, PhDPrincipal Investigator - University of Pittsburgh
University of Pittsburgh
2 Previous Clinical Trials
228 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have difficulty walking ¼ mile or climbing 10 steps without resting.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 26th, 2021

Last Reviewed: October 29th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.