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Behavioral Intervention

Supervised Exercise for Transplant Recipients

N/A

Recruiting

Led By Shannon McCurdy, MD

Research Sponsored by Abramson Cancer Center of the University of Pennsylvania

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from date of randomization until the date of first documented discharge from the hospital, assessed up to 100 months

Awards & highlights

Study Summary

This trial will determine if supervised exercise can improve outcomes for people undergoing a type of stem cell transplant. Up to 72 people will take part.

Who is the study for?

This trial is for older adults (60+) who are either pre-frail or frail and are planning to undergo or have undergone an allogeneic hematopoietic cell transplant (HCT) due to a blood cancer. Participants will be split into two groups: one that starts the exercise program before HCT and another that begins after HCT.Check my eligibility

What is being tested?

The study is testing if a supervised exercise program can improve health outcomes for those receiving allogeneic HCT. It's a pilot study, meaning it's preliminary research to see if the idea is feasible. Subjects will be divided into two cohorts based on when they start exercising relative to their transplant procedure.See study design

What are the potential side effects?

Since this trial involves an exercise program rather than medication, side effects may include typical physical activity-related issues such as muscle soreness, fatigue, or injury. The intensity of these side effects would vary depending on individual health status.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from date of randomization until the date of first documented discharge from the hospital, assessed up to 100 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from date of randomization until the date of first documented discharge from the hospital, assessed up to 100 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and from date of randomization until the date of first documented discharge from the hospital, assessed up to 100 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Median number of exercise sessions delivered pre-HCT and post-HCT.

Proportion of enrolled subjects who participate in the supervised exercise program

Secondary outcome measures

1-year and 2-year OS

1-year and 2-year PFS

6-month and 1-year overall mortality

+2 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Cohort B (Rehab)Experimental Treatment1 Intervention

All patients 60 years and older upon discharge from their initial hospital stay for HCT will attend at least weekly exercise sessions with a physical therapist and be given an exercise program to complete at home with sessions continued through Day +100 after HCT.

Group II: Cohort A (Prehab)Experimental Treatment1 Intervention

Pre-frail and frail subjects will attend at least twice weekly exercise sessions with a physical therapist and be given an exercise program to complete at home prior to admission for HCT. Patients enrolled in this cohort can continue on to Cohort B.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Abramson Cancer Center of the University of PennsylvaniaLead Sponsor

359 Previous Clinical Trials

104,992 Total Patients Enrolled

Abramson Cancer Center at Penn MedicineLead Sponsor

387 Previous Clinical Trials

145,592 Total Patients Enrolled

Shannon McCurdy, MDPrincipal InvestigatorPenn Medicine

1 Previous Clinical Trials

20 Total Patients Enrolled

Media Library

Exercise Program (Cohort A Prehab) (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05612789 — N/A

Transplant Research Study Groups: Cohort A (Prehab), Cohort B (Rehab)

Transplant Clinical Trial 2023: Exercise Program (Cohort A Prehab) Highlights & Side Effects. Trial Name: NCT05612789 — N/A

Exercise Program (Cohort A Prehab) (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05612789 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this trial currently recruiting participants?

"As per the details published on clinicaltrials.gov, this medical trial is not enrolling participants at present. Initially posted on November 1st 2022 and last edited 8 days later, no patients are being recruited currently; however 3 other studies remain open to volunteers."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Improve Outcomes for Older Allogeneic Transplant Recipients

2023. "Improve Outcomes for Older Allogeneic Transplant Recipients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05612789.