Home-Based Exercise for Chronic Kidney Disease

Recruiting at 1 trial location

Overseen By Merin Thomas

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Baylor College of Medicine

Disqualifiers: Pulmonary disease, Angina, Heart failure, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

15 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial tests if home-based exercise can improve physical function in frail or pre-frail kidney transplant candidates. Participants will use simple equipment at home to follow a personalized exercise plan. The goal is to enhance their strength, balance, and overall health.

Research Team

Elizabeth C Lorenz, MD

Principal Investigator

Baylor College of Medicine

Eligibility Criteria

This trial is for adults over 18 with any stage of chronic kidney disease who are frail or pre-frail, as measured by specific criteria. They must be able to consent to research and pass a submaximal exercise test if not approved for kidney transplantation. Those with severe heart, lung conditions, or needing multiple organ transplants cannot join.

Inclusion Criteria

Consenting to research

I am considered frail or almost frail based on my health assessment.

I have chronic kidney disease.

Exclusion Criteria

I failed the exercise test and am not approved for a kidney transplant.

I am under 18 years old.

I have serious health issues like heart problems or need for constant oxygen.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2 weeks

1 visit (in-person)

Exercise Intervention

Participants complete an 8-week home-based exercise program with pedal exerciser and resistance bands, including weekly phone calls with an exercise physiologist

8 weeks

Weekly phone calls

Follow-up

Participants are monitored for changes in physical function, frailty, and quality of life after the exercise intervention

4 weeks

Treatment Details

Interventions

• 8 week home-based exercise program

Trial Overview The study tests an 8-week home-based exercise program's effectiveness in improving physical function, frailty parameters, SPPB scores (a measure of balance and mobility), quality of life, activity levels, and reducing hospitalizations among kidney transplant candidates.

Participant Groups

Group I: Intervention Experimental Treatment 1 Intervention

Participants will be asked to complete an 8-week home-based exercise intervention

Who Is Running the Clinical Trial?

Baylor College of Medicine

Lead Sponsor

Trials

1,044

Recruited

6,031,000+

Mayo Clinic

Collaborator

Trials

3,427

Recruited

3,221,000+