Counterpressure Maneuvers for Fainting
(DETECT-ED Trial)
Trial Summary
Do I have to stop taking my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications. It seems likely that you can continue your medications, but you should confirm with the study team.
What data supports the idea that Counterpressure Maneuvers for Fainting is an effective treatment?
The available research does not provide any data specifically supporting the effectiveness of Counterpressure Maneuvers for Fainting. The studies mentioned focus on different conditions and treatments, such as gait improvement in stroke patients and surgical approaches for cerebral palsy, but do not address Counterpressure Maneuvers for Fainting.12345
What safety data exists for counterpressure maneuvers for fainting?
The safety data for counterpressure maneuvers (CPM) for fainting is limited but suggests potential benefits. Studies show that CPM can improve cardiovascular responses, such as increasing blood pressure and heart rate, which may help prevent syncope. However, practical limitations, like recognizing an impending faint, may restrict their daily use. Specific maneuvers like leg crossing, muscle tensing, and squatting have been shown to increase cardiac output and blood pressure, potentially preventing vasovagal syncope. The use of external counterpressure garments, like the 'Anti-G-Suit,' has also been effective in treating postural hypotension by increasing peripheral resistance and venous return. Overall, while CPMs show promise, more research is needed to fully understand their safety and efficacy in real-world settings.678910
Is the treatment Counterpressure Maneuvers for fainting promising?
What is the purpose of this trial?
The investigators will assess the efficacy of clinically recommended counterpressure maneuvers (CPM) in preventing syncope for paediatric patients. Participants presenting to the emergency department (ED) will first provide written informed consent. In stage I, they will be asked to complete a brief survey documenting the presentation of their syncopal episode, and any prodromal symptoms they experienced. Participants that consent to the second stage of the study will either receive usual care (control arm) or training in counter pressure maneuvers alongside usual care (intervention arm; leg crossing, bending, arm tensing). These patients will be followed for one years time, and will be asked to complete monthly surveys detailing their syncopal and presyncopal recurrence. Medical records will be accessed over the duration of the study to identify any changes in medical diagnosis.
Research Team
Shubhayan Sanatani, MD
Principal Investigator
University of British Columbia
Eligibility Criteria
This trial is for kids aged 6-18 who've fainted recently and show up at the emergency room between 10 am and 10 pm. They should be able to understand English to fill out surveys. Kids with heart rhythm problems, head injuries, seizures, drug overdoses, or certain fainting conditions without warning signs can't join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Stage I: Presentation of Syncope
Participants complete a survey documenting their syncopal episode and prodromal symptoms
Stage II: Treatment
Participants receive either usual care or training in counterpressure maneuvers alongside usual care
Follow-up
Participants are monitored for syncopal recurrence and other outcomes
Treatment Details
Interventions
- Counterpressure Maneuvers
- Usual Care
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dr. Victoria Claydon
Lead Sponsor
University of British Columbia
Collaborator
Simon Fraser University
Collaborator
Provincial Health Services Authority
Collaborator