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Standardized Dialysis for Acute Kidney Injury (Recover-AKI Trial)

N/A
Recruiting
Led By Samuel A Silver
Research Sponsored by Samuel Silver
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Plans for continued intermittent hemodialysis or sustained low efficiency dialysis treatments
Received ≥2 sessions of any dialysis modality for presumed AKI
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Recover-AKI Trial Summary

This trial will compare a standardized dialysis strategy to usual care in order to evaluate feasibility for AKI patients receiving dialysis.

Who is the study for?
This trial is for patients who have had acute kidney injury and received at least two dialysis sessions, with plans to continue. It's not for those on dialysis for over 90 days, with certain pre-existing conditions like severe chronic kidney disease or specific acute renal diseases, recent kidney transplant recipients, or pregnant individuals.Check my eligibility
What is being tested?
The study compares a standardized dialysis strategy (S2D2) against the usual care where each patient's primary nephrologist decides the treatment. The aim is to see if it's feasible to do a larger trial on this approach in patients recovering from acute kidney injury.See study design
What are the potential side effects?
While specific side effects are not listed here, typical risks of dialysis can include low blood pressure, muscle cramps, itching, sleep problems and infections. The structured approach may alter these risks but details would be provided during the consent process.

Recover-AKI Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am planning to continue with my dialysis treatments.
Select...
I have undergone at least 2 dialysis treatments for acute kidney injury.

Recover-AKI Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Fidelity
Recruitment
Secondary outcome measures
Dialysis-Free Days
Hypotensive Event on Dialysis
Other outcome measures
Arrhythmia on Dialysis

Recover-AKI Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Standardized Dialysis and Structured Discontinuation (S2D2)Experimental Treatment1 Intervention
Prescription to minimize dialysis-induced ischemia and standardize dialysis discontinuation
Group II: Usual CareActive Control1 Intervention
Dialysis prescription ordered by their primary nephrologist/intensivist.

Find a Location

Who is running the clinical trial?

Samuel SilverLead Sponsor
1 Previous Clinical Trials
400 Total Patients Enrolled
Unity Health TorontoOTHER
537 Previous Clinical Trials
447,439 Total Patients Enrolled
5 Trials studying Acute Kidney Injury
3,522 Patients Enrolled for Acute Kidney Injury
Samuel A SilverPrincipal InvestigatorQueen's University
1 Previous Clinical Trials
400 Total Patients Enrolled

Media Library

Standardized Dialysis and Structured Discontinuation (S2D2) Clinical Trial Eligibility Overview. Trial Name: NCT04948476 — N/A
Acute Kidney Injury Research Study Groups: Standardized Dialysis and Structured Discontinuation (S2D2), Usual Care
Acute Kidney Injury Clinical Trial 2023: Standardized Dialysis and Structured Discontinuation (S2D2) Highlights & Side Effects. Trial Name: NCT04948476 — N/A
Standardized Dialysis and Structured Discontinuation (S2D2) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04948476 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this clinical experiment currently open?

"According to clinicaltrials.gov, this study is actively enrolling participants and has been since it was initially posted on April 12th 2022. It underwent its most recent revision on the 28th of that same month."

Answered by AI

What is the current participation rate of this experiment?

"Affirmative. The trial is currently in search of participants, as evidenced by information available on clinicaltrials.gov. This study was first made public on April 12th 2022 and has seen an update recently issued on April 28th 2022; it requires 100 recruits for its single medical centre location."

Answered by AI
~4 spots leftby Jun 2024