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Somatostatin Analog

Low dose SRL + weekly Pegvisomant for Acromegaly

N/A
Waitlist Available
Led By Shlomo Melmed, MD
Research Sponsored by Cedars-Sinai Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 weeks
Awards & highlights

Study Summary

This trial will compare the effectiveness of two different combinations of drugs to see if a lower dose of one drug can achieve the same results as a higher dose of the same drug.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cost Effectiveness

Trial Design

3Treatment groups
Active Control
Group I: Low dose SRL + weekly PegvisomantActive Control3 Interventions
Low dose of SRL monthly Octreotide LAR 10mg Lanreotide 60mg Weekly Pegvisomant (40-120mg/week)
Group II: High dose SRL + weekly PegvisomantActive Control3 Interventions
High dose of SRL monthly Octreotide LAR 30mg Lanreotide 120mg Weekly Pegvisomant (40-120mg/week)
Group III: Low dose SRL + daily PegvisomantActive Control3 Interventions
Low dose of SRL monthly Octreotide LAR 10mg Lanreotide 60mg Daily Pegvisomant (15-60mg/day)

Find a Location

Who is running the clinical trial?

Cedars-Sinai Medical CenterLead Sponsor
500 Previous Clinical Trials
164,787 Total Patients Enrolled
8 Trials studying Acromegaly
287 Patients Enrolled for Acromegaly
Shlomo Melmed, MDPrincipal Investigator - Cedars-Sinai Medical Center
Cedars-Sinai Medical Center, Sound Physicians Platinum Group Pc
University Of Cape Town (Medical School)
7 Previous Clinical Trials
1,475 Total Patients Enrolled
2 Trials studying Acromegaly
163 Patients Enrolled for Acromegaly

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Acromegaly Combination Treatment Study
Shlomo Melmed, MD 2012. "Acromegaly Combination Treatment Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01538966.
~6 spots leftby May 2025
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