Treatment for Healthy Subjects (HS)

Phase-Based Estimates
1
Effectiveness
1
Safety
Mayo Clinic, Rochester, MN
Eligibility
18+
All Sexes
Eligible conditions
Healthy Subjects (HS)

Study Summary

This study is evaluating whether a specific diet may help reduce inflammation and improve gut health.

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Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 1 secondary outcome in patients with Healthy Subjects (HS). Measurement will happen over the course of 4 weeks.

4 weeks
Change in gut microbial alpha diversity based on Shannon index
Urinary Excretion of Lactulose and 13C-Mannitol

Trial Safety

Safety Estimate

1 of 3

Trial Design

1 Treatment Groups

Control

This trial requires 70 total participants across 1 different treatment groups

This trial involves a single treatment. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 4 weeks
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 4 weeks for reporting.

Who is running the study

Principal Investigator
P. C. K. M.
Purna C. Kashyap MBBS, Principal Investigator
Mayo Clinic

Closest Location

Mayo Clinic - Rochester, MN

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 2 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Adults ≥ 18 years old
On a baseline diet characterized by: Fiber intake of < 15g/day, > 18% of daily calories from protein

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can healthy subjects (hs) be cured?

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The majority of hs in the current study show the capacity to respond to standardized neurocognitive tests by showing no significant decline in performance after a 3- to 6-month follow-up period, in contrast to patients with schizophrenia. Although the current study sample was composed entirely of patients in the early phases of schizophrenia, the results are consistent with suggestions that deficits in normal neurocognitive functioning may have a central causative role in schizophrenia.

Unverified Answer

What causes healthy subjects (hs)?

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Results from a recent clinical trial suggest that healthy subjects in the population as a whole might display the same genetic basis as the schizophrenics, but it is possible that some healthy individuals might have a protective factor against the development of schizophrenia. The data imply that schizophrenia could be caused by the effect of unknown genes or by environmental risk factors.

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How many people get healthy subjects (hs) a year in the United States?

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About 3.3 million hs will be diagnosed with diabetes or cancer in 2022. A total of 3,813,812 hs will be diagnosed with lung disease or a smoking related illness in 2022, of whom 23% will die. At least 25% of those will be smokers. For every 1,000 patients with lung disease or a smoking related illness, 7 will die from lung diseases or a smoking related illness in 2022.

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What is healthy subjects (hs)?

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Healthy subjects are characterized as a population that is assumed to have a general health background, which is mainly defined by absence of pathological findings and no prior or current psychiatric disorders.

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What are common treatments for healthy subjects (hs)?

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Most common treatments in healthy subjects are nonpharmacological. Exercise is a common treatment in both genders and can improve blood lipids. In men, statins may reduce the risk of coronary heart disease, but more research is needed.

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What are the signs of healthy subjects (hs)?

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For the majority of the signs in the healthy subjects a specific cause is not identified as the etiology is undefined. It is suggested that some of the observed symptoms may be linked to the physiological changes of ageing.

Unverified Answer

Does treatment improve quality of life for those with healthy subjects (hs)?

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No statistical differences were found between the 2 groups in regard to physical functioning, social, and spiritual functioning. Given the high prevalence of chronic health conditions in the present population, a larger multicenter randomized control trial would provide insight into the real effects on health status of treatments aimed at improving the health of patients.

Unverified Answer

What are the common side effects of treatment?

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Findings from a recent study, the common side effects of treatment tended to vary with the age of the patient. This information is helpful because physicians have the ability to customize their patients' treatment based on this information.

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Is treatment typically used in combination with any other treatments?

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Data from a recent study provided evidence of the impact of the treatment combination on the treatment. It seems that the effect of the other treatments on the treatment itself is significant to the treatment outcome.

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How serious can healthy subjects (hs) be?

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We demonstrated that if a healthy patient was suffering from a severe clinical condition, their physicians could expect that more medical expertise would be needed, therefore leading to an increased use of diagnostic exams and procedures.

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What is the primary cause of healthy subjects (hs)?

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The major finding from this study is that in a large group of adults, a history of trauma and psychiatric disorders are a significant risk factors for the development of healthy subjects. However, the major finding is more controversial because there may be no link between healthy subjects and PTSD patients.

Unverified Answer

What does treatment usually treat?

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Despite the fact that treatment of infectious syndromes is often not a direct concern in primary care, we found that the majority of treatment interventions in primary care were directed at these common problems.

Unverified Answer
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