Livionex Toothpaste for Dental Plaque
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial uses Livionex® toothpaste to help children undergoing cancer treatments maintain better oral hygiene. These children are targeted because their treatments make it difficult for them to keep their mouths clean, increasing their risk of infections. The toothpaste works by reducing plaque and inflammation, which may help prevent serious infections.
Do I need to stop my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications.
How does Livionex® Dental Gel differ from other treatments for dental plaque?
Livionex® Dental Gel is unique because it contains 2.6% edathamil, which is designed to improve the surface microhardness and microstructure of enamel, potentially offering a novel approach to dental plaque management compared to traditional toothpastes that primarily focus on cleaning and polishing teeth.12345
Who Is on the Research Team?
Pamela Den Besten, DDS, MS
Principal Investigator
School of Dentistry, UC San Francisco
Are You a Good Fit for This Trial?
This trial is for children receiving chemotherapy, radiation, or Hematopoietic Stem Cell Transplantation (HSCT) who can follow the study's procedures. They and their parents must be willing to participate and sign consent forms. It's not for those with an allergy to edathamil or multiple hygiene/cosmetic products.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use Livionex or PreviDent 5000 plus/Tom's of Maine toothpaste for daily teeth brushing
Follow-up
Participants are monitored for safety and effectiveness after treatment, including plaque and gingival index assessments
What Are the Treatments Tested in This Trial?
Interventions
- Livionex® Dental Gel
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor