Esophageal String Test (EST) for Eosinophilic Esophagitis
Phase-Based Progress Estimates
Effectiveness
Safety
Mayo Clinic Arizona, Scottsdale, AZ
Eosinophilic Esophagitis+1 More
Esophageal String Test (EST) - DiagnosticTestEligibility
18+
All Sexes
What conditions do you have?
Select
Eligibility
18+
All Sexes
What conditions do you have?
Select
Study Summary
The purpose of this research is to determine if detergents in everyday products such as toothpaste make the lining of the esophagus leaky and cause allergic inflammation.
Eligible Conditions
- Eosinophilic Esophagitis
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 4 Secondary · Reporting Duration: Baseline, 15 minutes after teeth brushing
Baseline, 15 minutes after teeth brushing
Change in Mucosal impedance 15 minutes after exposure
Baseline, 30 minutes after teeth brushing
Change in Mucosal impedance 30 minutes after exposure
Baseline, 45 minutes after teeth brushing
Change in Mucosal impedance 45 minutes after exposure
Baseline, 60 minutes after teeth brushing
Change in Mucosal impedance 60 minutes after exposure
Baseline, approximately 60 minutes after teeth brushing
Change in IL-33 levels
Trial Safety
Safety Progress
Trial Design
1 Treatment Group
Toothpaste detergents with Eosinophilic Esophagitis Testing
1 of 1
Experimental Treatment
10 Total Participants · 1 Treatment Group
Primary Treatment: Esophageal String Test (EST) · No Placebo Group · N/A
Toothpaste detergents with Eosinophilic Esophagitis TestingExperimental Group · 3 Interventions: Esophageal String Test (EST), High Resolution Esophageal Manometry (HREM), Colgate · Intervention Types: DiagnosticTest, DiagnosticTest, Other
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Esophageal String Test (EST)
2018
N/A
~30
Trial Logistics
Trial Timeline
Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, 15 minutes after teeth brushing
Closest Location: Mayo Clinic Arizona · Scottsdale, AZ
2005First Recorded Clinical Trial
2 TrialsResearching Eosinophilic Esophagitis
150 CompletedClinical Trials
Who is running the clinical trial?
Mayo ClinicLead Sponsor
2,860 Previous Clinical Trials
3,686,151 Total Patients Enrolled
24 Trials studying Eosinophilic Esophagitis
1,509 Patients Enrolled for Eosinophilic Esophagitis
Benjamin Wright, MDPrincipal InvestigatorMayo Clinic
Eligibility Criteria
Age 18+ · All Participants · 2 Total Inclusion Criteria
Mark “yes” if the following statements are true for you:You are a healthy, normal, young adult.
About The Reviewer
Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.
Popular Clinical Trials
Top Clinical Trials in Cities
Relevant Clinical Trials
Unbiased Results
We believe in providing patients with all the options.Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.Back to top
Conditions
Cancer Related
Treatments