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Smoking counseling, Varenicline for Smoking

Phase 4
Waitlist Available
Led By Frances Chung, FRCPC
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after treatment unitl one month after the end of treatment
Awards & highlights

Study Summary

This study is a randomized, double-blind, placebo-controlled clinical trial which evaluates the efficacy of preoperative smoking counseling and varenicline (a medication approved by Health Canada and FDA for quitting smoking) to provide long term smoking cessation (i.e., abstinence for at least one year) in surgical patients. The primary hypothesis is as follows: "A significant percentage of surgical patients will be receptive to smoking cessation interventions in the pre-admission clinic and will refrain from smoking at 24 and 52 weeks after starting the treatment." The secondary hypothesis is as follows: "Patients who receive interventions but do not quit smoking will have reduced number of cigarettes consumed/day or improved their readiness to quit smoking at 24 and 52 weeks after starting the treatment."

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after treatment unitl one month after the end of treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and after treatment unitl one month after the end of treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
"stage of change" (determined by Prochaska and DiClemente's Model)
Number of cigarettes consumed per day over the past week prior to the assessment date.
Point prevalence of smoking cessation (those who have quitted smoking and have not smoked in the past week prior to the assessment date).
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Smoking counseling, VareniclineExperimental Treatment2 Interventions
Group II: Smoking counseling, PlaceboPlacebo Group2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Smoking counseling
2015
N/A
~40
Varenicline
FDA approved

Find a Location

Who is running the clinical trial?

PfizerIndustry Sponsor
4,567 Previous Clinical Trials
10,911,584 Total Patients Enrolled
11 Trials studying Smoking
3,264 Patients Enrolled for Smoking
University Health Network, TorontoLead Sponsor
1,468 Previous Clinical Trials
484,200 Total Patients Enrolled
3 Trials studying Smoking
696 Patients Enrolled for Smoking
Frances Chung, FRCPCPrincipal InvestigatorAnesthesia Department, Toronto Western Hospital, University of Toronto
2 Previous Clinical Trials
416 Total Patients Enrolled
1 Trials studying Smoking
296 Patients Enrolled for Smoking

Frequently Asked Questions

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~17 spots leftby Apr 2025