Treatment for Degenerative Disc Disease
This trial will compare the effects of tranexamic acid to placebo in patients undergoing lumber interbody fusion surgery.
3 Primary · 0 Secondary · Reporting Duration: Up to 7 days
2 Treatment Groups
1 of 2
1 of 2
300 Total Participants · 2 Treatment Groups
Primary Treatment: Treatment · Has Placebo Group · Phase 2
Who is running the clinical trial?
Age 18 - 90 · All Participants · 4 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Has this medication been deemed safe by the FDA?
"This treatment received a score of 2, as there is some evidence pointing to its safety but it has not been proven effective yet." - Anonymous Online Contributor
Could I possibly qualify to take part in this experiment?
"The study team is looking for 300 individuals that have intervertebral disc degeneration and meet the following conditions: being between 18-90 years old, having an American Spinal Injury Association (ASIA) Impairment Scale anesthesia risk of I to IV, having a Body Mass Index (BMI) below 35, needing 2 or more levels of posterior lumbar interbody fusion for DDD. This includes PLIF or TLIF., and finally candidates must have failed conservative management such as physical therapy (PT) or occupational therapy (OT)." - Anonymous Online Contributor
Are there precedents for this proposed treatment plan?
"At the moment, there are 68 different clinical trials underway that are studying this treatment. Of these active studies, 29 are in Phase 3 and they're based all over the world in 304 different locations with a majority being concentrated in Kansas City, Kansas." - Anonymous Online Contributor
Under what circumstances would this medication be given to a patient?
"This medical intervention is used to treat hyperfibrinolysis. It can also be employed in cases like hemophilia, where there is abnormal bleeding, and during tooth extractions." - Anonymous Online Contributor
Are there any more open spots in this clinical trial for patients who wish to enroll?
"The clinicaltrials.gov listing for this trial shows that it is open and recruiting patients. This 300-person study was posted on August 1st, 2020 and last updated on October 13th, 2020 at a single site." - Anonymous Online Contributor
Could you tell me if people who are under 25 years old can participate in this clinical trial?
"This study's age requirements are that potential participants must be between 18-90 years old." - Anonymous Online Contributor
How many people are in this clinical trial?
"That is correct, the online clinicaltrial.gov registry has this listed as an ongoing study that began recruitment on 8/1/2020. The last update was 10/13/2022 and they are looking for 300 participants at 1 locations." - Anonymous Online Contributor