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Antifibrinolytic Agent

Tranexamic acid injection for Postoperative Pain

Phase 3

Waitlist Available

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up surveys will be completed by patients at 1 week, 1 month, 3 months post-operatively

Awards & highlights

Study Summary

This trial will compare post-op results of patients who receive tranexamic acid with those who receive traditional local anesthetic during upper lid blepharoplasty surgery.

Eligible Conditions

Postoperative Pain
Bruises

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ surveys will be completed by patients at 1 week, 1 month, 3 months post-operatively

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~surveys will be completed by patients at 1 week, 1 month, 3 months post-operatively

This trial's timeline: 3 weeks for screening, Varies for treatment, and surveys will be completed by patients at 1 week, 1 month, 3 months post-operatively for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

change in bruising

change in bruising a survey to rate pain

Side effects data

From 2021 Phase 3 trial • 1226 Patients • NCT04733157

Vomiting

Dizziness

Nausea

100%

80%

60%

40%

20%

Study treatment Arm

Study Group/Group A_(Tranexamic Acid)

Control Group/Group B_(Placebo)

Trial Design

1Treatment groups

Experimental Treatment

Group I: Blepharoplasty patientExperimental Treatment1 Intervention

Patient receives LA in one eye and LA with TXA in the other eye. They are blinded. They compare eyes without knowing which one received the TXA.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Tranexamic acid injection

2021

Completed Phase 4

~3060

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor

1,585 Previous Clinical Trials

917,191 Total Patients Enrolled

5 Trials studying Postoperative Pain

297 Patients Enrolled for Postoperative Pain

Media Library

Tranexamic acid injection (Antifibrinolytic Agent) Clinical Trial Eligibility Overview. Trial Name: NCT04724772 — Phase 3

Postoperative Pain Research Study Groups: Blepharoplasty patient

Postoperative Pain Clinical Trial 2023: Tranexamic acid injection Highlights & Side Effects. Trial Name: NCT04724772 — Phase 3

Tranexamic acid injection (Antifibrinolytic Agent) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04724772 — Phase 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are they currently looking for more volunteers for this experiment?

"This is an active clinical trial that was first posted on February 20th, 2020 and updated most recently on April 5th, 2022 according to the website clinicaltrials.gov"

Answered by AI

How many total patients will be enrolled in this research project?

"That is correct. As of today, the clinical trial indicated on clinicaltrials.gov is still recruiting patients that it first posted about on February 20th, 2020. The study requires 40 more participants and is being conducted at 1 location."

Answered by AI

Are there any other studies that have looked into Tranexamic acid injection?

"Right now, there are 68 ongoing studies for Tranexamic acid injection with 29 of them in the third phase. The majority of research facilities conducting these trials are situated in Kansas City, but there are a total of 304 clinical trial sites for this medication."

Answered by AI

For what purpose is Tranexamic acid injection most commonly applied?

"Tranexamic acid injection is most often used to treat hyperfibrinolysis, but it can also help with conditions like hemophilia and bleeding from tooth extractions."

Answered by AI

Has the United States' Food and Drug Administration cleared Tranexamic acid for use?

"Tranexamic acid injection is considered safe based on its Phase 3 status, meaning that there is some data supporting efficacy and multiple rounds of data supporting safety."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Use of Tranexamic Acid in Blepharoplasties

Craig Brawley 2020. "Use of Tranexamic Acid in Blepharoplasties". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04724772.