← Back to Search

Attention Bias Retraining for Obesity

Phase 2

Waitlist Available

Led By Jack A Yanovski, M.D.

Research Sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

BMI at or above the 85th percentile for age and sex according to the Centers for Disease Control US Standards (101)

Age between 12 and 17 years (at the start of the study)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2-weeks

Awards & highlights

Study Summary

This trial is studying the relationship between eating patterns, body weight, and how the brain reacts to different images in teens.

Who is the study for?

This trial is for right-handed, overweight female teens aged 12-17 with a BMI at or above the 85th percentile. It's not for those who are pregnant, use substances regularly, have had significant brain injuries, are in weight loss programs or psychotherapy for eating behavior, take medications affecting weight/eating (except on a case-by-case basis), have serious psychiatric disorders or major illnesses.Check my eligibility

What is being tested?

The study tests if training attention away from unhealthy foods using a smartphone program can affect eating patterns and body weight in teens. Participants will undergo various assessments including MRI scans and blood tests over six visits spanning approximately eight months.See study design

What are the potential side effects?

Since this trial involves non-invasive procedures like attention retraining via smartphone and standard medical assessments (MRI scan, blood draw), side effects may be minimal but could include discomfort from fasting before visits or anxiety during MRI scanning.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My BMI is in the top 15% for my age and sex.

Select...

I am between 12 and 17 years old.

Select...

I am female.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2-weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2-weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2-weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in laboratory measured attention bias

Neural activity during attention bias task

Secondary outcome measures

Change in attention bias

Change in eating pattern

Change in reaction time to palatable foods

Trial Design

4Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Booster TrainingExperimental Treatment1 Intervention

3 months after the randomized program is completed, each subject can elect to use open-label attention bias retraining for 2 weeks

Group II: AB RetrainingExperimental Treatment1 Intervention

Active treatment - the probe always replaces the neutral picture. There is a perfect correlation between picture type and probe location.

Group III: Booster Training - active comparatorActive Control1 Intervention

3 months after the randomized program is completed, each subject can elect to use open-label attention bias retraining for 2 weeks

Group IV: AB ControlPlacebo Group1 Intervention

Control condition - the probe is equally likely to replace the food picture and the neutral picture. There is no correlation between picture type and probe location, and no training of attention should occur.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Lead Sponsor

1,963 Previous Clinical Trials

2,674,659 Total Patients Enrolled

104 Trials studying Obesity

96,990 Patients Enrolled for Obesity

Jack A Yanovski, M.D.Principal InvestigatorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

23 Previous Clinical Trials

7,186 Total Patients Enrolled

14 Trials studying Obesity

3,827 Patients Enrolled for Obesity

Media Library

Attention Bias Retraining Clinical Trial Eligibility Overview. Trial Name: NCT02977403 — Phase 2

Obesity Research Study Groups: Booster Training, AB Control, AB Retraining, Booster Training - active comparator

Obesity Clinical Trial 2023: Attention Bias Retraining Highlights & Side Effects. Trial Name: NCT02977403 — Phase 2

Attention Bias Retraining 2023 Treatment Timeline for Medical Study. Trial Name: NCT02977403 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has Attention Bias Retraining received government authorization for use?

"Attention Bias Retraining is judged to be a safe intervention with a score of 2 due to its Phase 2 clinical trial status which indicates that safety has been established but efficacy remains unproven."

Answered by AI

How many volunteers are participating in this clinical research?

"Affirmative. The clinical trial's details which were originally uploaded on February 10th 2017, can be accessed via clinicaltrials.gov and reveals that the research is currently in its recruitment phase with 120 individuals required from a single site."

Answered by AI

Is recruitment currently being conducted for this investigation?

"Affirmative. Clinicaltrials.gov confirms that this medical experiment, which was initiated on February 10th 2017 is actively searching for participants. Approximately 120 patients need to be enlisted from 1 site."

Answered by AI

Am I able to partake in this medical research?

"To be eligible for this research, applicants must possess eating disorders and binge-eating tendencies while being within 12 to 21 years of age. Ultimately, the study seeks 120 participants in total."

Answered by AI

Does this research endeavor accommodate participants over 30 years old?

"According to the inclusion criteria, adolescents between 12 and 21 years old are eligible for this clinical trial. For individuals under 18 there are 280 trials that may be suitable while those over 65 have access to 1078 research opportunities."

Answered by AI