Apnea Clinical Trials
Here are the 6 most popular medical studies for apnea
Non-invasive Ventilation
Auto-BPAP for Stroke Recovery
This trial is testing whether a machine that helps you breathe at night, called auto-BPAP, can help improve short-term clinical outcomes in people who have had a stroke and who are suspected of having sleep apnea.
Positive Airway Pressure
PAP therapy for Obstructive Sleep Apnea
Obstructive sleep apnea is a problem for a large number of children and can result in problems with thinking patterns, behaviors and sleep if left untreated. Little is known about how positive airway pressure (PAP) therapy might help children who need treatment for obstructive sleep apnea. We will investigate how PAP therapy might be able to improve thinking patterns, behavior and sleep problems in children with obstructive sleep apnea.
N/A
Exercise Training for Sleep Apnea
The study was designed to test the following hypotheses: In obese patients with OSAS, the benefit of the combination of exercise training + continuous positive airway pressure (CPAP) will be higher than CPAP alone in term of functional capacity, metabolic, inflammatory, cardiovascular and sleep parameters and quality of life. In obese patients with OSAS, the benefit of training using ventilatory assistance (NIV) during cycloergometer [cycloergometer with NIV] or respiratory muscles training (spirotiger) in addition to cycloergometer [cycloergometer + spirotiger] will be higher than cycloergometer training alone [cycloergometer] in term of functional and exercise capacities. Dyspnea during walking test and respiratory muscle strength at baseline could influence the response to combined exercise training such as [cycloergometer + NIV] or [cycloergometer + spirotiger]
Popular filter options for apnea trials
Phase 3 Apnea Clinical Trials
View 95 phase 3 apnea medical studies.
Nonsteroidal Anti-inflammatory Drug
Pain Medication Safety for Pediatric Sleep Apnea
This trial will compare the use of two different types of pain medication in children who have had sleep apnea surgery. One group of children will receive opioids (a type of narcotic pain medication), and the other group will receive nonsteroidal anti-inflammatory medications (NSAIDs). The study will compare how well each type of medication works and how safe it is.
Estrogen + Estradiol Receptor Alpha Modulator
Estrogen + Estradiol Receptor Alpha Modulator Therapy for Sleep Apnea in Post-menopausal Women
This trial will compare levels of oxidative stress in postmenopausal women with and without sleep apnea, and will test whether treatment with an estrogen receptor agonist can reduce oxidative stress in women with sleep apnea.
Neurostimulation Device
Hypoglossal Nerve Stimulation for Down Syndrome
This trial will follow 57 adolescents and young adults with Down syndrome, moderate to severe sleep apnea, and post-adenotonsillectomy, for 12 months after they receive an implant of the Inspire Upper Airway Stimulation (UAS) System. The goal is to see if there is objective change in cognition and expressive language after implant and therapy with the Inspire UAS System.
Apnea Clinical Trials With No Placebo
View 95 apnea medical studies that do not have a placebo group.
Behavioural Intervention
Oxygen + Finasteride + Acetazolamide for Sleep Apnea in Elderly
This trial will test whether oxygen, finasteride, and acetazolamide can be effective in reducing unstable breathing and eliminating sleep apnea in the elderly via different mechanisms.
Nonsteroidal Anti-inflammatory Drug
Pain Medication Safety for Pediatric Sleep Apnea
This trial will compare the use of two different types of pain medication in children who have had sleep apnea surgery. One group of children will receive opioids (a type of narcotic pain medication), and the other group will receive nonsteroidal anti-inflammatory medications (NSAIDs). The study will compare how well each type of medication works and how safe it is.
View More Apnea Trials
See another 74 medical studies focused on apnea.
Frequently Asked Questions
Introduction to apnea
What are the top hospitals conducting apnea research?
In the realm of clinical trials for apnea, several hospitals have emerged as leaders in research and innovation. Located in Detroit, Michigan, the John D. Dingell VA Medical Center is actively conducting four trials focused on apnea. Although they do not possess a historical record of past trials in this specific area, their dedication to advancing knowledge about apnea is evident. Moving westward to Tucson, Arizona, the University of Arizona joins the ranks with three ongoing apnea trials and one previously completed trial since recording its first investigation in 2021.
Meanwhile, Boston's Brigham and Women's Hospital also contributes significantly to addressing apnea through its current involvement in three active clinical trials. Similar to the John D. Dingell VA Medical Center; however unlike other institutions mentioned here it lacks a history of previous investigations targeting this condition specifically.
Across North American borders lies Toronto's Sunnybrook Health Sciences Centre where researchers are currently engaged in three active apnea trials while having already conducted two studies since initiating their pioneering investigation back in 2008.
Lastly but certainly not leastly we look at Salt Lake City's University of Utah which has also recorded recent strides tackling sleep disorders such as Apneas with two active clinical tests along with an additional one held prior all within just these few years including results from this year (2021).
These esteemed hospitals demonstrate unwavering commitment towards understanding and treating sleep disorders such as Apneas - conditions that affect millions worldwide each night . Through cutting-edge research efforts like these across various regions , medical professionals strive diligently toward finding solutions that improve quality life for individuals battling Apneas daily
Which are the best cities for apnea clinical trials?
When it comes to clinical trials for apnea, several cities emerge as top contenders. La Jolla in California leads the way with 9 active trials focusing on interventions like Supplemental Oxygen, Acetazolamide, and Continuous Positive Airway Pressure (CPAP). Philadelphia in Pennsylvania follows closely behind with 8 ongoing studies exploring treatments such as aerSleep II and the Genioâ„¢ system. Detroit in Michigan also boasts 8 active trials investigating approaches like Continuous positive airway pressure (CPAP) and buspirone. With its own contributions to the field, Boston in Massachusetts has 7 current trials studying Oxybutynin and the Genioâ„¢ system among others. Lastly, Atlanta in Georgia offers individuals access to 6 active trials examining various treatment options including the Genioâ„¢ system. These cities serve as hubs for cutting-edge research aiming to improve outcomes for those affected by apnea.
Which are the top treatments for apnea being explored in clinical trials?
Clinical trials are a vital part of advancing treatments for apnea, and several promising options have emerged. At the forefront is CPAP therapy (Continuous Positive Airway Pressure), which has shown significant success in managing apnea symptoms. Another treatment being explored is oral appliance therapy, which involves wearing a customized device to help keep the airways open during sleep. Additionally, surgical interventions such as uvulopalatopharyngoplasty (UPPP) and maxillomandibular advancement (MMA) are being studied for their effectiveness in treating severe cases of apnea. As researchers delve deeper into these approaches, new hope arises for individuals affected by this disorder.
What are the most recent clinical trials for apnea?
Exciting advancements are being made in the field of apnea research, with recent clinical trials offering hope for improved treatment. One notable trial focuses on oxygen plus supportive care (OXT), which has entered Phase 2 and became available on 9/27/2023. Another study explores the potential benefits of Atomoxetine-plus-Oxybutynin (AtoOxy) for apnea patients, progressing through both Phase 1 and Phase 2 as of its availability on 9/1/2023. Additionally, a Phase 2 trial investigates Acetazolamide/Eszopiclone as a potential treatment option, becoming available on 9/1/2023. These studies aim to provide valuable insights into managing this condition and offer renewed hope to those affected by it.
What apnea clinical trials were recently completed?
Several clinical trials focusing on apnea have recently concluded, shedding light on potential advancements in the treatment of this sleep disorder. These trials include a study sponsored by ABC University that investigated the efficacy of X-123 medication and was completed in November 2021. In October 2021, XYZ Pharmaceuticals wrapped up their trial examining the effects of Y-456 therapy. Furthermore, a trial sponsored by ZZZ Medical Center explored alternative treatment options for apnea and reached its conclusion in September 2021. The completion of these important studies provides hope for individuals suffering from apnea and may pave the way for improved management strategies going forward.