Motivational Enhancement Therapy for Heart Failure and Sleep Apnea

JA
CP
Overseen ByCinthya Pena Orbea, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: The Cleveland Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether a new telemedicine approach, called Telemedicine Intensive Motivational Enhancement (TIME), can improve adherence to sleep apnea treatment compared to traditional doctor visits. It targets individuals recently diagnosed with both heart failure and sleep apnea. The study aims to determine if this approach improves sleep and heart health and reduces hospital visits. It suits those with heart failure who are new to sleep apnea treatment and willing to use a PAP machine, which helps keep airways open during sleep. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance treatment options for patients with heart failure and sleep apnea.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this telemedicine motivational enhancement is safe for heart failure and sleep apnea patients?

Research has shown that using telemedicine to boost motivation is generally well-received. Studies suggest this method can help people adhere to their sleep apnea treatment after hospital discharge. Few reports of serious side effects suggest it is safe for most patients. The trial is currently focused on evaluating the treatment's effectiveness rather than just its safety. This indicates the treatment is considered safe enough to test its effectiveness, which may reassure those considering joining the trial.12345

Why are researchers excited about this trial?

Researchers are excited about the Telemedicine Intensive Motivational Enhancement for heart failure and sleep apnea because it offers a fresh approach to improving patient adherence to positive airway pressure (PAP) therapy. Unlike the standard of care that typically involves in-person visits, this treatment leverages telemedicine to provide motivational support remotely. This approach not only increases accessibility for patients who may find regular doctor visits challenging but also aims to boost adherence to PAP therapy, which is crucial for managing sleep apnea effectively. By enhancing patient motivation through remote support, researchers hope this method will lead to better health outcomes and improved quality of life for patients.

What evidence suggests that Telemedicine Intensive Motivational Enhancement is effective for heart failure and sleep apnea?

Research has shown that Telemedicine Intensive Motivational Enhancement (TIME), which participants in this trial may receive, helps people with heart failure and sleep apnea follow their treatment plans more effectively. Studies have found that those using TIME are more likely to continue using their Positive Airway Pressure (PAP) machines after leaving the hospital, which is crucial for managing sleep apnea. This method can also improve heart health. Additionally, starting TIME early has been linked to better patient-reported outcomes, such as improved sleep quality and overall well-being. This makes TIME a promising option for people dealing with both heart failure and sleep apnea. Participants in this trial will either receive TIME or continue with standard care, which involves regular follow-up for sleep apnea with their provider.14678

Who Is on the Research Team?

CP

Cinthya Pena Orbea, MD

Principal Investigator

The Cleveland Clinic

Are You a Good Fit for This Trial?

This trial is for patients hospitalized with acute decompensated heart failure (ADHF) who are newly diagnosed with obstructive sleep apnea (OSA, REI ≥5), have not used PAP therapy before, and agree to use it. Excluded are those with central predominant apnea, unstable vital signs, dementia, prior PAP use, inability to consent or participate in video calls.

Inclusion Criteria

I am diagnosed with acute decompensated heart failure.
I have not received any treatment and agree to start PAP therapy.
I have been diagnosed with obstructive sleep apnea.
See 1 more

Exclusion Criteria

I have received PAP therapy before or am currently on it.
My oxygen levels drop below 87% without aid or I need more than 2L of O2 at night.
You have problems with memory and thinking.
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive Auto-CPAP therapy and motivational enhancement intervention or standard care

6 months
2 visits (in-person) at 2 weeks and 2 months, additional telemedicine sessions

Follow-up

Participants are monitored for PAP adherence and health outcomes, with booster sessions at 4 months

6 months
Booster phone call at 4 months

What Are the Treatments Tested in This Trial?

Interventions

  • Telemedicine Intensive Motivational Enhancement
Trial Overview The study tests if a telemedicine program providing intensive motivational support (TIME) can improve adherence to positive airway pressure (PAP) therapy over standard care. It also looks at the effect on patient outcomes and hospital readmissions within 6 months after discharge.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Telemedicine Intensive Motivational EnhancementExperimental Treatment1 Intervention
Group II: Standard of Care with providerActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

The Cleveland Clinic

Lead Sponsor

Trials
1,072
Recruited
1,377,000+

American Academy of Sleep Medicine

Collaborator

Trials
29
Recruited
3,000+

Citations

Post-Discharge Telemedicine Motivational Enhancement ...It was hypothesized that motivational enhancement (ME) via a telemedicine intensive approach improves PAP adherence post-discharge in hospitalized patients with ...
Acute Decompensated Heart Failure and OSA | Clinical ...Assess the effect of early telemedicine integrated with motivational enhancement (TIME) vs standard of care on patient reported outcomes including Functional ...
0551 Telemedicine Motivational Enhancement in Heart Failure ...... Heart Failure (ADHF) with Obstructive Sleep Apnea (OSA) confers improvement of cardiovascular outcomes, PAP adherence remains exceedingly low. We ...
Telemedicine for obstructive sleep apnea syndromeTelemedicine (TM) is a new medical service model in which computer, communication, and medical technologies and equipment are used to provide “face-to-face” ...
0551 Telemedicine Motivational Enhancement in Heart ...0551 Telemedicine Motivational Enhancement in Heart Failure and Sleep Apnea Randomized Clinical Trial ... Sleep Apnea (OSA) is associated with improved outcomes.
0551 Telemedicine Motivational Enhancement in Heart ...Sleep Health and Safety ... 0551 Telemedicine Motivational Enhancement in Heart Failure and Sleep Apnea Randomized Clinical Trial Free.
1121 Post-Discharge Telemedicine Motivational ...We hypothesized that motivational enhancement (ME) via a telemedicine intensive approach improves PAP adherence post-discharge in hospitalized patients with ...
Heart Failure Management through TelehealthTelehealth holds the potential to drive substantial qualitative improvement in clinical practice through the development of patient-centered ...
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