This is a dual-site, double-blinded, randomized, crossover study design for SEEG-guided 4-lead DBS for treatment-refractory OCD, followed by open label stimulation for an additional 6 months. The study will be conducted in 3 stages: Stage 1 will consist of SEEG brain mapping and optimization of stimulation parameters. Stage 2 will consist of DBS surgery and further optimization of stimulation parameters. Stage 3 will be randomized, crossover treatment, followed by open label treatment.
6 Primary · 0 Secondary · Reporting Duration: Approximately 4 years
10 Total Participants · 2 Treatment Groups
Primary Treatment: SEEG Guided DBS ON-OFF (Stimulation-Sham) · Has Placebo Group · N/A
Age 22 - 65 · All Participants · 10 Total Inclusion CriteriaMark “Yes” if the following statements are true for you: