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Surgery With/Without Nerve Cutting for Wrist Ganglion

N/A

Waitlist Available

Led By Kenneth Taylor, MD

Research Sponsored by Kenneth Taylor, M.D.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Subjects who have chosen surgical management for their ganglion cyst diagnosis

Diagnosis of symptomatic dorsal wrist ganglion cyst (pain and limited ability to perform activities of daily living)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up preop to one year post-op

Awards & highlights

Study Summary

This trial is testing whether cutting a nerve during surgery to remove a wrist cyst improves post-operative pain and function.

Who is the study for?

This trial is for adults over 18 with painful dorsal wrist ganglion cysts affecting daily activities. Candidates must speak and understand English, be non-prisoners, able to follow the study plan, and have chosen surgery for their condition. It excludes those under 18, non-English speakers, prisoners, cognitively impaired individuals, anyone with prior wrist surgery or chronic instability in the affected wrist, neurological issues in that wrist, or who are pregnant.Check my eligibility

What is being tested?

The study compares two surgical methods for treating dorsal wrist ganglions: excision alone (DWG) versus excision plus partial denervation by cutting a sensory nerve branch (DWG/PIN). The goal is to see if adding nerve resection improves pain relief and function post-surgery.See study design

What are the potential side effects?

Potential side effects may include discomfort at the surgery site, possible nerve damage leading to altered sensation or weakness in the hand/wrist area. There might also be typical surgical risks like infection or scarring.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have chosen surgery to treat my ganglion cyst.

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I have a painful wrist cyst that limits my daily activities.

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I am 18 years old or older.

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I am not pregnant and identify as male or female.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ preop to one year post-op

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~preop to one year post-op

This trial's timeline: 3 weeks for screening, Varies for treatment, and preop to one year post-op for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pain behavior measured with the Patient-Reported Outcomes Measurement Information (PROMIS) Pain Behavior instrument

Pain interference measured with the Patient-Reported Outcomes Measurement Information (PROMIS) Pain Interference instrument

Pain measured with the Visual Analog Pain Scale (VAS)

+1 more

Secondary outcome measures

Change in strength utilizing finger lateral pinch measurements

Change in strength utilizing finger three-point pinch measurements

Change in strength utilizing finger tip pinch measurements

+6 more

Trial Design

2Treatment groups

Active Control

Group I: Dorsal wrist ganglion alone (DWG)Active Control1 Intervention

Dorsal wrist ganglion excision alone

Group II: DWG with PINActive Control1 Intervention

Dorsal wrist ganglion excision with posterior interosseus neurectomy (PIN)

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Kenneth Taylor, M.D.Lead Sponsor

2 Previous Clinical Trials

58 Total Patients Enrolled

Kenneth Taylor, MDPrincipal InvestigatorPenn State Health Milton S Hershey Medical Center

2 Previous Clinical Trials

58 Total Patients Enrolled

Media Library

Dorsal wrist ganglion alone (DWG) Clinical Trial Eligibility Overview. Trial Name: NCT04932122 — N/A

Muscle Atrophy Research Study Groups: Dorsal wrist ganglion alone (DWG), DWG with PIN

Muscle Atrophy Clinical Trial 2023: Dorsal wrist ganglion alone (DWG) Highlights & Side Effects. Trial Name: NCT04932122 — N/A

Dorsal wrist ganglion alone (DWG) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04932122 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this investigation still available to prospective participants?

"This research is no longer open to recruiting, as indicated on clinicaltrials.gov. It was first posted December 1st, 2022 and last updated July 13th, 2022; however, 210 other medical trials are currently looking for participants."

Answered by AI

What is the ultimate goal of this clinical investigation?

"Over the Preop to One Year Post-Op period, this trial is assessing physical function by way of a Disabilities of the Arm, Shoulder and Hand questionnaire (QuickDASH). Secondary analysis will evaluate strength changes through finger lateral pinch measurements, hand grip measures with a dynamometer, and three-point pinch assessments."

Answered by AI

Recent research and studies

Hand SurgeryJournal

Current Treatment of Ganglion of the Wrist

Ho, P. C., J. Griffiths, W. N. Lo, C. H. Yen, and L. K. Hung. 2001. “Current Treatment of Ganglion of the Wrist”. Hand Surgery. World Scientific Pub Co Pte Lt. doi:10.1142/s0218810401000540.

The Journal of Hand SurgeryJournal

Distal Posterior Interosseous Nerve Syndrome

Carr, Daniel, and Philip Davis. 1985. “Distal Posterior Interosseous Nerve Syndrome”. The Journal of Hand Surgery. Elsevier BV. doi:10.1016/s0363-5023(85)80165-9.

Hand SurgeryJournal

The Simple Wrist Ganglion — More Than A Minor Surgical Procedure?

Faithfull, D. K., and B. G. Seeto. 2000. “The Simple Wrist Ganglion — More Than A Minor Surgical Procedure?”. Hand Surgery. World Scientific Pub Co Pte Lt. doi:10.1142/s0218810400000235.

Journal of the American Academy of Orthopaedic SurgeonsJournal