This trial is evaluating whether Therapeutic diet and lifestyle will improve 2 primary outcomes and 5 secondary outcomes in patients with Clinically Isolated Syndrome (CIS). Measurement will happen over the course of change from baseline to 12 months.
This trial requires 44 total participants across 2 different treatment groups
This trial involves 2 different treatments. Therapeutic Diet And Lifestyle is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"We found that 1 in every 3 Americans would experience that disease at some time in their life. The risk of developing the disorder was lowest in the first decade of life and rose steadily until around age 75." - Anonymous Online Contributor
"Patients of any age may be treated with corticosteroids. There is also significant interest in newer agents for treatment of MS. There is a clear absence of treatments for MS that are available outside of North America." - Anonymous Online Contributor
"The cause of MS is not known, and there are numerous theories. The prevailing idea is that the disease results from “demyelination” of the white matter of the brain, but more recent research suggests that the process can go on in the absence of white matter damage; the presence of “tumour-like” lesions; or immune-based damage to other parts of the brain; or a combination of these. We would probably have better knowledge if it were not very difficult to detect these abnormalities. There are numerous possible explanations for the disease. To date, none have been proved to be correct, and there will probably always be more research necessary in this field." - Anonymous Online Contributor
"The most effective therapy in MS is probably to try to slow the progressive course of MS and to try improving the quality of life. If, however, the condition is not so severe that the quality of life is severely affected, the treatment to try to prevent, or even treat, fatigue, depressive symptoms, and other disability-related symptoms is worthwhile." - Anonymous Online Contributor
"Multiple sclerosis is a disease that mainly affects the central nervous system (CNS). It can affect many systems throughout the body and over time, cause disabling symptoms, and, in many cases, result in disability.\n" - Anonymous Online Contributor
"A complete clinical examination in people with an MS diagnosis is essential for detecting a number of the early signs of the disease. These include abnormal eye movements, unsteady walking, decreased vision, fatigue, mood swings and decreased cognition.\n" - Anonymous Online Contributor
"These data indicate no evidence for linkage of MS to a chromosome region containing a known MHC gene, such as a gene encoding major histocompatibility complex class II or TNF or IFN regulatory factor 1." - Anonymous Online Contributor
"Therapeutic diet and lifestyle may have a potentially beneficial effect in the management of MS. However, the lack of information may lead clinicians to consider placebo effects." - Anonymous Online Contributor
"Which I am too late to say but that is the most recent survey so far...about 10years ago, so I'm still researching to find out if that's the most current information available. (the average age at onset of MS has also been changing. It used to be about 27 years, then in the past decade this has been 20.5. Now that's not good... ) My feeling is that perhaps it's actually not going to change. In fact, I think people are going to be MS'ing as they have for more than 30years and still are..." - Anonymous Online Contributor
"We conclude that an enriched dietary pattern and a healthy lifestyle cannot be recommended. The health benefits achieved with a balanced diet are not due to improvements in metabolic parameters of participants with MS." - Anonymous Online Contributor
"Overall, we found that dietary and lifestyle modification were relatively infrequently added to existing MS treatments, and usually did not contribute significantly to the therapeutic effect of the therapeutic regimen." - Anonymous Online Contributor
"Dietary and physical interventions have made significant progress in the treatment of MS. Diet is considered an adjuvant; some patients may benefit from nutritional intervention, either with nutritional supplements or with nutritional programs. MS diet should be individualized and should be used in rehabilitation clinics. There are many possibilities for improvement of diet. It is time to get closer to patients, know how they eat, which foods they get, what is their dietary approach (including quantity and quality of food), which supplements are used, etc. It is important to understand how the new therapeutics will affect the dietary program; some of them will be complementary." - Anonymous Online Contributor