← Back to Search

Amino Acid Supplement

Branched Chain Amino Acids for Concussion (HIT HEADS Trial)

Phase 2
Waitlist Available
Led By Sage Myers, MD
Research Sponsored by Children's Hospital of Philadelphia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up days 3-6, 7-10, 11-14
Awards & highlights

HIT HEADS Trial Summary

This trial will test whether BCAA supplements can help people recover from concussions.

HIT HEADS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~days 3-6, 7-10, 11-14
This trial's timeline: 3 weeks for screening, Varies for treatment, and days 3-6, 7-10, 11-14 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Reaction time difference between drug and placebo groups
Secondary outcome measures
Clinical symptoms
Compliance and Adherence to Treatment
Neurocognitive recovery
+3 more

HIT HEADS Trial Design

5Treatment groups
Experimental Treatment
Placebo Group
Group I: Branched Chain Amino Acids (7.5g BID)Experimental Treatment1 Intervention
7.5 grams of BCAA's will be administered twice-daily for 21 days
Group II: Branched Chain Amino Acids (27g BID)Experimental Treatment1 Intervention
27 grams of BCAA's will be administered twice-daily for 21 days
Group III: Branched Chain Amino Acids (22.5g BID)Experimental Treatment1 Intervention
22.5 grams of BCAA's will be administered twice-daily for 21 days
Group IV: Branched Chain Amino Acids (15g BID)Experimental Treatment1 Intervention
15 grams of BCAA's will be administered twice-daily for 21 days
Group V: PlaceboPlacebo Group1 Intervention
Placebo will be administered orally twice daily for 21 days
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Branched Chain Amino Acids
2019
Completed Phase 2
~60

Find a Location

Who is running the clinical trial?

Children's Hospital of PhiladelphiaLead Sponsor
708 Previous Clinical Trials
8,581,261 Total Patients Enrolled
The Dana FoundationOTHER
17 Previous Clinical Trials
942 Total Patients Enrolled
Main Line HealthOTHER
20 Previous Clinical Trials
6,737 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any other reports on the efficacy of Branched Chain Amino Acids?

"Presently, 6 clinical trials of Branched Chain Amino Acids are underway with 1 research project in its final phase. The majority of these experiments originate from Columbus, Ohio; nevertheless, 23 other trial sites exist for this medication."

Answered by AI

What criteria must potential participants meet to be involved in this experiment?

"This clinical trial is enrolling 50 individuals, aged between 11 and 34 years old who have sustained a traumatic brain injury. Other eligibility criteria includes: being of any gender/race, having access to email and the internet on a daily basis (if female), passing an urine pregnancy test, demonstrating the capacity to grant informed consent or assent in case they are minors and having been diagnosed by a certified medical practitioner within 72 hours prior to enrollment."

Answered by AI

Is participation in this trial available at the present time?

"Affirmative. The clinical trial registry on clinicaltrials.gov attests to this medical investigation's ongoing recruitment process, which began on January 1st 2014 and was last revised on March 22nd 2022. This research is looking for 50 volunteers from a single site."

Answered by AI

How many individuals are participating in the research project?

"Affirmative. Information hosted on clinicaltrials.gov indicates that this medical study, which was initially posted in January 1st 2014, is actively inviting participants to join the trial. The team plans to recruit a total of 50 patients from one site location."

Answered by AI

Is the age requirement for this trial restricted to individuals over 30 years old?

"This trial has specified age requirements of 11 to 34 years old, with 29 studies recruiting participants younger than 18 and 38 focused on individuals above 65."

Answered by AI

Has the FDA endorsed Branched Chain Amino Acids for medicinal use?

"The safety of Branched Chain Amino Acids was rated a 2, as the drug is only in Phase 2 trials and has yet to demonstrate its efficacy."

Answered by AI

What medical applications are associated with Branched Chain Amino Acids?

"Branched Chain Amino Acids are frequently implemented to treat conditions of parenteral nutrition, as well as gestational term birth, uremia, and various protein metabolism disorders."

Answered by AI

Who else is applying?

What state do they live in?
Florida
How old are they?
18 - 65
What site did they apply to?
The Children's Hospital of Philadelphia
What portion of applicants met pre-screening criteria?
Met criteria
~4 spots leftby Apr 2025