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Dutasteride + Dietary Interventions for Prostate Cancer

N/A

Waitlist Available

Led By Vincent Fradet, MD

Research Sponsored by CHU de Quebec-Universite Laval

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0-6-12 months

Awards & highlights

Study Summary

This trial will test whether marine omega-3 fatty acids and 5-alpha-reductase inhibitors can help low-risk prostate cancer patients by slowing the progression of the disease.

Who is the study for?

This trial is for individuals with low-risk prostate cancer who are candidates for active surveillance and have given informed consent. It's not open to those currently taking fish oil supplements or NSAIDs.Check my eligibility

What is being tested?

The study is testing the effectiveness of marine omega-3 fatty acids (dietary intervention) and Dutasteride (a drug), separately, in slowing down the progression of low-risk prostate cancer.See study design

What are the potential side effects?

Dutasteride may cause sexual side effects, such as decreased libido, erectile dysfunction, or ejaculation disorders. Dietary interventions could lead to changes in digestion or allergies.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0-6-12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0-6-12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-6-12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Effects of the Interventions on Lipid Metabolism From Blood and Prostatic Microenvironment

Secondary outcome measures

Determine the Clinical Utility of Urine-Based Cancer Markers in the Context of Interventions to Reduce Cancer Progression

Effect of Interventions on Gene Expression Profile

Effects of Interventions on Hormonal Metabolism

Trial Design

2Treatment groups

Experimental Treatment

Group I: Drug intervention firstExperimental Treatment1 Intervention

Intake of 5α-Reductase Inhibitor

Group II: Dietary intervention firstExperimental Treatment1 Intervention

The dietary intervention will be aimed to increase intake of ω-3 long chain fatty acids and to reduce intake of saturated and trans fatty acids.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

CHU de Quebec-Universite LavalLead Sponsor

167 Previous Clinical Trials

107,037 Total Patients Enrolled

13 Trials studying Prostate Cancer

3,842 Patients Enrolled for Prostate Cancer

Prostate Cancer CanadaOTHER

9 Previous Clinical Trials

7,406 Total Patients Enrolled

7 Trials studying Prostate Cancer

7,282 Patients Enrolled for Prostate Cancer

Vincent Fradet, MDPrincipal InvestigatorLaval University

Media Library

Dietary intervention Clinical Trial Eligibility Overview. Trial Name: NCT01653925 — N/A

Prostate Cancer Research Study Groups: Dietary intervention first, Drug intervention first

Prostate Cancer Clinical Trial 2023: Dietary intervention Highlights & Side Effects. Trial Name: NCT01653925 — N/A

Dietary intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT01653925 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this experiment recruiting participants who are older than thirty years of age?

"This trial is open to individuals aged 35 and over, up to 75 years of age."

Answered by AI

Is there room to accommodate new participants in this research endeavor?

"This clinical trial is not seeking further candidates. It was first announced in November 2010 and last amended on March 14th 2022. For those looking for similar studies, 1252 trials related to prostate cancer are currently accepting new patients; 6 of which employ Dutasteride as an intervention."

Answered by AI

What is the upper limit of participants in this medical research?

"This medical trial is no longer recruiting. It was initially posted on November 1st 2010 and last revised March 14th 2022. As of now, there are 1252 active clinical trials with a focus on prostate cancer and 6 specifically looking at the efficacy of dutasteride as an intervention that are enrolling patients."

Answered by AI

What criteria must be met for a patient to qualify for this clinical research?

"To enroll in this study, patients aged 35-75 with prostate cancer must meet the following criteria: low risk prostatic neoplasms, candidate for active surveillance, and signing of an informed consent. A total of 120 participants are needed."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Molecular Mechanisms of Dutasteride and Dietary Interventions to Prevent Prostate Cancer and Reduce Its Progression

2010. "Molecular Mechanisms of Dutasteride and Dietary Interventions to Prevent Prostate Cancer and Reduce Its Progression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01653925.

All > Prostate Cancer