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Study Summary
This trial is testing a new gene therapy to see if it can help people with severe Angina Pectoris by directly injecting it into their heart.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Find a Location
Who is running the clinical trial?
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- I am eligible for standard procedures to restore blood flow.I cannot come back for follow-up appointments.I have severe chest pain that doesn't improve with medication.I cannot or will not undergo heart-related tests involving catheters or nuclear methods.My treatment areas can be safely targeted for therapy.I have had a stroke or a mini-stroke in the last 60 days.I have had recent issues with diabetic eye disease or wet age-related vision loss.I am not willing to use condoms for a year after treatment.I am not on medications that pose a high health risk.I experience chest pain that limits my ability to exercise, but it's not heart-related.I have uncontrolled heart rhythm problems.I had a major heart attack within the last 60 days.I have not had a recent heart attack or unstable chest pain.I have a severe condition that limits my ability to exercise.I have severe narrowing of my aortic valve or a mechanical heart valve.I have had cancer or currently have cancer.I felt chest pain during my exercise test.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this trial taking place at a significant number of hospitals across the country?
"The trial is running in Davenport, Dallas and Phoenix as well as 32 other locations. To reduce the amount of travel needed, patients are encouraged to select a clinic that is close to their home."
What are the risks and side effects associated with this treatment?
"This Phase 2 trial lacks data confirming the efficacy of the proposed treatment, but there is some evidence supporting its safety--our team gave it a score of 2."
Are there any unfilled vacancies for this clinical trial?
"The clinical trial isn't recruiting patients right now but was posted on 8/1/2004 and last edited on 4/18/2006 according to clinicaltrials.gov. Right now, there are 54 other studies that are accepting patients."
Are there any specific requirements to qualify for this clinical trial?
"The aim of this study is to enroll 404 individuals that have angina pectoris and are between 18-0 years old. Additionally, it is crucial that potential participants meet the following prerequisites: Experiencing signs or symptoms of angina during an exercise tolerance test (ETT) and having procedurally acceptable targeted treatment zones."
Does this clinical trial have an age limit?
"Patients that wish to enroll in this clinical trial must be aged 18-0. If a patient is under the age of 18, there are 3 other trials they may be eligible for. For patients over 65, there are 54 other trials available."
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