CLINICAL TRIAL

Microwave ablation for Lung Cancer

Recruiting · 18+ · All Sexes · Calgary, Canada

This study is evaluating whether a surgery which reduces blood flow in a stomach artery leads to significant weightloss.

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About the trial for Lung Cancer

Eligible Conditions
Neoplasms · Lung Neoplasms · Neoplasm Metastasis

Treatment Groups

This trial involves 2 different treatments. Microwave Ablation is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase 1 & 2 and have already been tested with other people.

Main TreatmentA portion of participants receive this new treatment to see if it outperforms the control.
Microwave ablation
PROCEDURE
Control TreatmentAnother portion of participants receive the standard treatment to act as a baseline.

About The Treatment

Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Microwave ablation
2011
N/A
~500

Eligibility

This trial is for patients born any sex aged 18 and older. You must have received 1 prior treatment for Lung Cancer or one of the other 2 conditions listed above. There are 7 eligibility criteria to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Patients who are not amenable to surgery, radiation therapy (SBRT) or chemotherapy (or patient refusal) are typically treated with best supportive care. show original
, and prostate cancers are the most common sites of distant metastasis Distant metastases from various cancers are most commonly found in the lungs, colorectal region, breasts, and bone marrow. show original
The patient has a median estimate survival of more than one year, as determined by the treating physician. show original
The patient has a limited and/or controlled extra-pulmonary disease, which will be determined by a multidisciplinary consensus. show original
The patient will have documentation from the surgeon and/or radiation oncologist stating that the patient is not able to have surgery and SBRT. show original
ECOG 0-1
.> The text states that there are five lesions in either lung. show original
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Odds of Eligibility
Unknown<50%
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial

Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 1 month post treatment
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 1 month post treatment.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Microwave ablation will improve 3 primary outcomes and 1 secondary outcome in patients with Lung Cancer. Measurement will happen over the course of 1 week post treatment.

Rate of adverse outcomes following microwave ablation
1 WEEK POST TREATMENT
Proportion of patients experiencing local adverse events at one week definitively related to the mwa procedure.
Efficacy of microwave ablation of lung lesions
1 MONTH POST TREATMENT
To demonstrate efficacy by measuring the proportion of patients demonstrating absence of residual tumor on follow up CT at 1 month after MWA.
Rate of technical success
1 MONTH POST TREATMENT
Proportion of patients in whom technical success of MWA was achieved by assessing completion of ablation on CT at the time of the procedure, indicated by replacement of tumor by ground glass change (including a 5mm ablation zone in normal surrounding lung parenchyma).
Re-treatment rate.
1 MONTH POST TREATMENT
To determine the proportion of patients needing re-treatment for recurrent tumor at 1 month post MWA.

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of lung cancer?

There are many possible signs of lung cancer. The signs can include an increase in coughing up blood, blood in the stool or urine, weight loss, unintentional weight loss, breathlessness or a cough. There are other possible signs and a variety of signs may occur.

Anonymous Patient Answer

Can lung cancer be cured?

The five-year overall survival rate was 74%, but the disease had already metastasized in more than half of the patients at diagnosis. Most patients with advanced stage disease and early disease recurrence survive an average of 4.3 years after metastatic recurrence. Lung cancer has few if any curative therapies.

Anonymous Patient Answer

What is lung cancer?

It is unknown where the lung originated, but it is believed to have been where the lungs take in air. When the lung receives air it expands and moves. Lung cancer is the result of abnormal cell growth. Some people are at an increased risk for lung cancer. The risk depends on the age of the person in addition to things such as where they live and their genotype of genetic code. Smoking, a known risk factor for lung cancer is also linked to lung cancer.

Anonymous Patient Answer

What causes lung cancer?

Lung cancer is caused by many factors, and we can identify them by the following scheme: environmental factor (smoking), environmental factor (pesticides, pesticides), infection, and genetic risk factors. In other words, cigarette smoking is the biggest factor in lung cancer.

Anonymous Patient Answer

What are common treatments for lung cancer?

More than one-third of all [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer) survivors have symptoms attributable to their cancer that were managed through nonsurgical means. Most of those who require surgical care are treated with curative intent. There is no evidence for a benefit from surgery beyond the curative intent.

Anonymous Patient Answer

How many people get lung cancer a year in the United States?

A total of 10,623 [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer) events were detected in 2017 from which 56% were in men. Around 8,620 men were diagnosed with lung cancer in the same year. Lung cancer is the 7th-most common cancer in men and the 4th-most-prevalent cancer in women. Around 1.5 million Americans a year get lung cancer making it the 11th-most-common cancer. The numbers in this article refer specifically to cancer cases rather than disease cases. The estimates of lung cancer deaths are more difficult to calculate as lung cancer also has cases in which death cannot be determined.

Anonymous Patient Answer

Is microwave ablation safe for people?

Microwave energy is a safe treatment modality in selected patients and can be a good alternative to surgery, especially in patients not suitable for resection due to age or poor general health.

Anonymous Patient Answer

What are the chances of developing lung cancer?

In a recent study, findings showed a positive correlation of the risk of developing any form of [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer) by age. The chances of developing lung cancer doubled almost four times for each decade after the age of 40 years. This is interesting because even with the advances in treatment, the chances of the development of lung cancer continues to increase, particularly with tobacco smoking which is the major cause of lung cancer and second largest cause of cancer death in the United States. Even though there seems to be an increase in cases across the board of all ages of the patients, it is the case for stages I and II that is most dangerous with more than 75% of survival rate that is still achievable in patients who have been diagnosed with an early stage of the disease.

Anonymous Patient Answer

Have there been any new discoveries for treating lung cancer?

There have been no new major breakthroughs since 2000. It is difficult to determine exactly what has changed because of the difficulty in accessing pertinent information. We can only look at anecdotal evidence. The medical reports from the last few years cite disappointing results when these were applied to patients with lung cancer. This might be as a result of treatment approaches being too conservative or too aggressive. Although there is some evidence that the chemotherapy regimen can increase patients' survival, it is important that patients' survival will still remain low after any kind of treatment. It is the most critical issue in the treatment of lung cancer, and it has not been improved significantly.

Anonymous Patient Answer

Who should consider clinical trials for lung cancer?

Recent findings provides evidence of both the lack of quality control within trials and the low rates of recruitment of patients into clinical trials. The implications of conducting good quality trials on the recruitment of patients with advanced or recurrent stages of tumors are discussed.

Anonymous Patient Answer

How serious can lung cancer be?

Lung cancer is an aggressive and serious disease and patients with lung cancer tend to die sooner or sooner than patients with other forms of cancer which are not so aggressive or serious.\nLung cancer's survival is worse in young and elderly patients, for women, for whites. Lung cancer often has a long latency time.

Anonymous Patient Answer

How quickly does lung cancer spread?

For unknown reasons, [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer) will not spread to the rest of the organs if it is localized to the lungs and to lymph nodes close to the site of primary tumor. Even if it spreads locally, it is unlikely to spread to distant organs if it is limited to the lung or lymph node at the same level; in fact, patients with lung cancer who have the disease limited to the lung are at higher risk of dying from other causes (such as pneumonia or cancer).

Anonymous Patient Answer
See if you qualify for this trial
Get access to this novel treatment for Lung Cancer by sharing your contact details with the study coordinator.