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Microwave Ablation

Microwave Ablation for Lung Cancer

N/A

Recruiting

Led By Jason Beattie, MD

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Target nodule/tumor which can be accessed via navigational bronchoscopy and confirmed location with cone beam CT scan intra-operatively

Participants must be at least 22 years old and able to provide consent

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 weeks

Awards & highlights

Study Summary

This trial is being done to see if the AveCure Flexible Microwave Ablation Probe is effective in destroying cancerous lung nodules that are up to 3 c m in size.

Who is the study for?

This trial is for adults over 22 with Stage I-II primary lung cancer, specifically solitary nodules up to 3 cm. They must have a confirmed type of malignancy and be candidates for surgery. Excluded are those with nodules under 1 cm, prior treatments on the nodule, contraindications to bronchoscopy, significant comorbidities, electronic implants, coagulopathy issues or participation in other lung cancer studies.Check my eligibility

What is being tested?

The study tests the effectiveness of the AveCure Flexible Microwave Ablation Probe on destroying cancerous lung nodules up to 3 cm. It involves microwave ablation (MWA) using this probe through navigational bronchoscopy and cone beam CT scan confirmation during operation.See study design

What are the potential side effects?

While specific side effects aren't listed here, generally microwave ablation can cause pain at the site of treatment, bleeding into the chest cavity or airways, collapse of part of a lung (pneumothorax), damage to surrounding organs or structures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My tumor can be reached and checked with a special lung biopsy technique.

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I am 22 years old or older and can give my consent.

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I am eligible for surgery to remove part of my lung.

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My lung cancer is in the early stages (Stage I or II) and involves a single nodule up to 3 cm.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pathological changes in the tumor tissue.

Rate of Planned Ablations.

Secondary outcome measures

Histological changes in lung tissue outside the zone of predicted ablation.

Immune-histochemical changes in the tumor tissue.

Trial Design

1Treatment groups

Experimental Treatment

Group I: AVECURE FLEXIBLE MICROWAVE ABLATION PROBE FOR LUNG NODULESExperimental Treatment1 Intervention

The research study procedures include screening for eligibility and study treatment including evaluations and follow up visits. Ablation Procedure- MWA will be used to treat solitary pulmonary nodules up to 3cm. CT scan will then be performed to evaluate the radiological changes 2 - 4 weeks after the ablation procedure. Surgery will be performed to remove the lung nodule and the tissue will be evaluated by pathology.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor

837 Previous Clinical Trials

13,010,262 Total Patients Enrolled

Dana-Farber Cancer InstituteOTHER

1,079 Previous Clinical Trials

340,970 Total Patients Enrolled

MedWaves, IncUNKNOWN

1 Previous Clinical Trials

10 Total Patients Enrolled

Media Library

AveCure Flexible Microwave Ablation Probe (Microwave Ablation) Clinical Trial Eligibility Overview. Trial Name: NCT05281237 — N/A

Lung Cancer Research Study Groups: AVECURE FLEXIBLE MICROWAVE ABLATION PROBE FOR LUNG NODULES

Lung Cancer Clinical Trial 2023: AveCure Flexible Microwave Ablation Probe Highlights & Side Effects. Trial Name: NCT05281237 — N/A

AveCure Flexible Microwave Ablation Probe (Microwave Ablation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05281237 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it still possible for participants to join this clinical experiment?

"Clinicaltrials.gov confirms that this trial, which was promulgated on June 1st 2022 and last updated 11th March of the same year, is not presently seeking participants. Nonetheless, there are 1636 other trials actively recruiting patients at this time."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Avecure Flexible Microwave Ablation Probe For Lung Nodules

Jason A Beattie 2022. "Avecure Flexible Microwave Ablation Probe For Lung Nodules". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05281237.