Psilocybin-assisted Psychotherapy for Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.
Will I have to stop taking my current medications?
Yes, you may need to stop taking certain medications. Participants must be free from regularly scheduled psychotropic medications for at least 2 weeks before the study, or 4 weeks for SSRIs. Some prescribed medications, like opiates and benzodiazepines, can continue if stable for a certain period before screening.
How is the drug psilocybin unique in treating anxiety and depression in cancer survivors?
Psilocybin is unique because it is used in combination with psychotherapy to provide rapid and long-lasting relief from anxiety and depression in cancer survivors, enhancing spiritual well-being and quality of life. Unlike traditional treatments, it involves a single high-dose session that can lead to significant improvements in mood and outlook, with effects lasting for months.12345
What data supports the effectiveness of the drug psilocybin for cancer survivors?
Who Is on the Research Team?
Moran Amit, MD, PHD
Principal Investigator
M.D. Anderson Cancer Center
Are You a Good Fit for This Trial?
This trial is for adult cancer survivors who are now free of disease but suffer from depression and/or anxiety. They must not have brain involvement, be fluent in English, able to travel for sessions, and agree to avoid certain substances. Excluded are those with a high suicide risk, recent severe depression before cancer diagnosis, pregnant women or without contraception use, vulnerable populations like children or cognitively impaired individuals.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive psilocybin-assisted psychotherapy for depression and/or anxiety
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Psilocybin
Find a Clinic Near You
Who Is Running the Clinical Trial?
M.D. Anderson Cancer Center
Lead Sponsor