Bethanechol for Pancreatic Cancer

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Columbia University Medical Center, New York, NYPancreatic CancerBethanechol - Drug
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This trial is testing a drug to see if it increases the chances of a successful surgery to remove a pancreatic tumor, as well as if it is safe and well tolerated.

Eligible Conditions
  • Pancreatic Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Similar Trials

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 36 months

36 months
Ki-67 expression in tumor cells
R0 resection rate

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Similar Trials

Trial Design

1 Treatment Group

Bethanechol
1 of 1

Experimental Treatment

37 Total Participants · 1 Treatment Group

Primary Treatment: Bethanechol · No Placebo Group · Phase 2

BethanecholExperimental Group · 3 Interventions: Bethanechol, Gemcitabine, nab-paclitaxel · Intervention Types: Drug, Drug, Drug
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Bethanechol
2009
Completed Phase 1
~10
Gemcitabine
2017
Completed Phase 3
~2070
nab-paclitaxel
2008
Completed Phase 4
~1290

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 36 months

Who is running the clinical trial?

Susan E. BatesLead Sponsor
Susan E Bates, MDPrincipal InvestigatorColumbia University
1 Previous Clinical Trials
18 Total Patients Enrolled

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are planning to receive chemotherapy before a main treatment.

Frequently Asked Questions

What is the projected enrollment for this trial?

"Affirmative. According to details available on clinicaltrials.gov, this trial began recruiting patients as of February 1st 2022 and has been modified since then. Currently, the study requires 37 individuals across a single site to partake in it." - Anonymous Online Contributor

Unverified Answer

Is enrollment for this study still available?

"As per the clinicaltrials.gov registry, this medical trial is actively searching for participants. It was first published on February 1st 2022 and later updated on March 2nd of the same year." - Anonymous Online Contributor

Unverified Answer

Has the FDA officially sanctioned Bethanechol for public consumption?

"Due to the lack of efficacy-related data, our analysts assigned bethanechol a safety rating of 2 out of 3." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.