Medical/Behavioral therapy for Coronary Artery Disease

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Coronary Artery DiseaseMedical/Behavioral therapy - Other
Eligibility
21 - 90
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether a personalized treatment plan based on biomarkers can help reduce the risk of complications for people with coronary artery disease.

Eligible Conditions
  • Coronary Artery Disease

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 5 Secondary · Reporting Duration: 5 years post intervention

5 years post intervention
All cause death
Year 1
Change in Biomarker Risk Score (BRS)
Year 5
Change in plasma levels of BNP
Change in plasma levels of hs-cTnI
Change in plasma levels of hsCRP
Change in plasma levels of suPAR
Year 5
Change in composite complications

Trial Safety

Trial Design

2 Treatment Groups

Usual Care Group
1 of 2
Optimization Group
1 of 2

Active Control

Experimental Treatment

450 Total Participants · 2 Treatment Groups

Primary Treatment: Medical/Behavioral therapy · No Placebo Group · N/A

Optimization Group
Other
Experimental Group · 1 Intervention: Medical/Behavioral therapy · Intervention Types: Other
Usual Care Group
Other
ActiveComparator Group · 1 Intervention: Standard of Care · Intervention Types: Other

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 5 years post intervention

Who is running the clinical trial?

Emory UniversityLead Sponsor
1,509 Previous Clinical Trials
2,705,719 Total Patients Enrolled
29 Trials studying Coronary Artery Disease
11,041 Patients Enrolled for Coronary Artery Disease
Arshed Quyyumi, MDPrincipal InvestigatorEmory University
11 Previous Clinical Trials
2,286 Total Patients Enrolled
1 Trials studying Coronary Artery Disease
25 Patients Enrolled for Coronary Artery Disease

Eligibility Criteria

Age 21 - 90 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Patients undergoing revascularization therapy or recent acute coronary syndrome (ACS) will be eligible for recruitment and will be recruited at least 4 weeks after admission for an ACS or percutaneous intervention and 3 months after coronary bypass graft surgery.