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Procedure

Standard Ablation Technique for Supraventricular Tachycardia (AVNRT Trial)

N/A
Recruiting
Research Sponsored by Jeffrey Moak
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Weight >15 kg
Age < 21 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during procedure- start to finish
Awards & highlights

AVNRT Trial Summary

This trial compares two methods for correcting a heart condition called AVNRT. The first, called the New Ablation Technique, uses low voltage and wave front collision mapping. The second, called the Standard Ablation Technique, uses an anatomical/electrogram approach.

Eligible Conditions
  • Supraventricular Tachycardia

AVNRT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

AVNRT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during procedure- start to finish
This trial's timeline: 3 weeks for screening, Varies for treatment, and during procedure- start to finish for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Primary end point - Number of lesions needed to achieve modification of slow AV nodal pathway
Secondary outcome measures
Secondary End points - Time from start to end of ablation lesion application(s), and total length of procedure.

AVNRT Trial Design

2Treatment groups
Active Control
Group I: Standard Ablation TechniqueActive Control1 Intervention
Ablation performed using the traditional anatomical / electrogram guided ablation approach.
Group II: New Ablation TechniqueActive Control1 Intervention
Will undergo ablation using voltage mapping and triangle of Koch propagation wave collision mapping. Ablation will be performed at or slightly above the site of wave front collision.

Find a Location

Who is running the clinical trial?

Jeffrey MoakLead Sponsor
1 Previous Clinical Trials
870 Total Patients Enrolled
University of Wisconsin, MadisonOTHER
1,180 Previous Clinical Trials
3,592,050 Total Patients Enrolled
University of LouisvilleOTHER
336 Previous Clinical Trials
75,640 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have joined the experiment thus far?

"This clinical trial necessitates the involvement of 300 patients that fit within their desired criteria. Patients will be able to join from multiple sites, including Univeristy of Iowa in Iowa City and University of Louisville in Louisville, Kentucky."

Answered by AI

In what geographic areas is this clinical research being conducted?

"This particular medical trial is recruiting patients at the University of Iowa in Iowa City, the University of Louisville in Louisville, and the Univeristy of Wisconsin located in Madison. Additionally, there are 5 other locations participating."

Answered by AI
Recent research and studies
Circulation: Arrhythmia and ElectrophysiologyJournal
Atrioventricular Nodal Reentrant Tachycardia in Patients with Congenital Heart Disease
Papagiannis, John, Daniel Joseph Beissel, Ulrich Krause, Michel Cabrera, Marta Telishevska, Stephen Seslar, Christopher Johnsrude, et al.. 2017. “Atrioventricular Nodal Reentrant Tachycardia in Patients with Congenital Heart Disease”. Circulation: Arrhythmia and Electrophysiology. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/circep.116.004869.
EuropaceJournal
Radiofrequency Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia in Children Aided by the Localisa Mapping System
Kammeraad, J. 2004. “Radiofrequency Catheter Ablation of Atrioventricular Nodal Reentrant Tachycardia in Children Aided by the Localisa Mapping System”. Europace. Oxford University Press (OUP). doi:10.1016/j.eupc.2004.02.004.
Pacing and Clinical ElectrophysiologyJournal
Low Temperature and Low Energy Radiofrequency Modification of Atrioventricular Nodal Slow Pathways in Pediatric Patients
RHODES, LARRY A., TAMMY S. WIEAND, and VICTORIA L. VETTER. 1999. “Low Temperature and Low Energy Radiofrequency Modification of Atrioventricular Nodal Slow Pathways in Pediatric Patients”. Pacing and Clinical Electrophysiology. Wiley. doi:10.1111/j.1540-8159.1999.tb00572.x.
EuropaceJournal
Treatment of Atrioventricular Nodal Re-entrant Tachycardia by Cryoablation with a 6 Mm-tip Catheter Vs. Radiofrequency Ablation
Chan, N. Y., N. S. Mok, C. L. Lau, Y. K. Lo, C. C. Choy, S. T. Lau, and Y. C. Choi. 2009. “Treatment of Atrioventricular Nodal Re-entrant Tachycardia by Cryoablation with a 6 Mm-tip Catheter Vs. Radiofrequency Ablation”. Europace. Oxford University Press (OUP). doi:10.1093/europace/eup121.
~63 spots leftby Apr 2025
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