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Corticosteroid

Intraarticular platelet rich plasma cervical facet injection for Neck Pain (PRICE Trial)

Phase 2 & 3
Waitlist Available
Led By Eldon Loh, MD
Research Sponsored by Lawson Health Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 1, 3 and 6 months (+ 9 and 12 months) if at least an ongoing 2 point reduction at 6 months
Awards & highlights

PRICE Trial Summary

This trial is testing whether a different type of injection (platelet-rich plasma, PRP) can provide longer-lasting pain relief for chronic neck pain compared to the current steroid injections.

PRICE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 1, 3 and 6 months (+ 9 and 12 months) if at least an ongoing 2 point reduction at 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 1, 3 and 6 months (+ 9 and 12 months) if at least an ongoing 2 point reduction at 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pain intensity
Proportion attaining 90% and 50% pain relief on Numeric Rating Scale
Proportion attaining at least a 2 point reduction in pain on Numeric Rating Scale
+1 more
Secondary outcome measures
Adverse Events
Patient reported function in the presence of neck pain
Patient's subjective satisfaction with the procedure
+2 more

PRICE Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Platelet Rich PlasmaExperimental Treatment1 Intervention
One time injection of 1.5-6cc of platelet rich plasma prepared from a blood sample into cervical facet joints. There is no trade/generic name
Group II: Dexamethasone Sodium PhosphateActive Control1 Intervention
Corticosteroid: 0.5 cc saline and 0.5cc of 10 mg/mL dexamethasone per facet joint (up to 6 mL total volume for 4 facet injections)

Find a Location

Who is running the clinical trial?

Lawson Health Research InstituteLead Sponsor
656 Previous Clinical Trials
413,373 Total Patients Enrolled
1 Trials studying Neck Pain
43 Patients Enrolled for Neck Pain
Eldon Loh, MDPrincipal InvestigatorSt. Joseph's Healthcare London
4 Previous Clinical Trials
329 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Why is Intraarticular platelet rich plasma cervical facet injection commonly given?

"ophthalmia, sympathetic is frequently treated with Intraarticular platelet rich plasma cervical facet injection. This medical intervention is also used to treat other conditions such as eye, branch retinal vein occlusion, and macular edema."

Answered by AI

Who else is applying?

What state do they live in?
Pennsylvania
Quebec
How old are they?
18 - 65
65+
What site did they apply to?
St. Joseph's Health Care London
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Typically responds via
Email
Recent research and studies
~13 spots leftby Apr 2025