← Back to Search

Retail Environments for Tobacco Smoking

N/A
Waitlist Available
Led By Emily Falk, PhD
Research Sponsored by Abramson Cancer Center at Penn Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between the ages of 21-65
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up for 822815, fmri scan day 1 (at least 2 weeks after initial enrollment); for 850796, fmri scan 1 (at least 6 weeks after initial enrollment)]
Awards & highlights
No Placebo-Only Group

Summary

This trial looks at how smoking affects the brain and behavior, as well as exposure to smoking in specific environments.

Who is the study for?
This study is for English-speaking smokers aged 21-65 who smoke at least 5 cigarettes daily for the past 6 months. Participants must own a smartphone, be fully vaccinated against COVID-19, and reside in PA, DE, NJ or the Philadelphia area for the next 3 months with limited absences.
What is being tested?
The trial aims to understand how smokers' brains and behaviors are influenced by their everyday environments, particularly retail spaces like convenience stores (7-11) and pharmacies (CVS).

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 21 and 65 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~for 822815, fmri scan day 1 (at least 2 weeks after initial enrollment); for 850796, fmri scan 1 (at least 6 weeks after initial enrollment)]
This trial's timeline: 3 weeks for screening, Varies for treatment, and for 822815, fmri scan day 1 (at least 2 weeks after initial enrollment); for 850796, fmri scan 1 (at least 6 weeks after initial enrollment)] for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Brain activity (measured by functional magnetic resonance imaging), in a priori regions of interest, in response to smoking vs nonsmoking cues (all 822815 participants and fMRI subset of 850796 participants)
Neural cue reactivity region definition (822815 participants and fMRI subset of 850796 participants)
Self-reported cigarette craving during the experimental manipulation period
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: CVS GroupExperimental Treatment1 Intervention
Participants visit CVS 5 times per week during the 4-week (20 store visits total) intervention period
Group II: 7-11 GroupExperimental Treatment1 Intervention
Participants visit 7-11 5 times per week during the 4-week (20 store visits total) intervention period
Group III: ControlActive Control1 Intervention
Participants are not asked to alter their behavior during the 4-week (0 store visits) intervention period

Find a Location

Who is running the clinical trial?

Abramson Cancer Center at Penn MedicineLead Sponsor
412 Previous Clinical Trials
164,678 Total Patients Enrolled
National Cancer Institute (NCI)NIH
13,886 Previous Clinical Trials
41,020,627 Total Patients Enrolled
University of PennsylvaniaLead Sponsor
2,067 Previous Clinical Trials
42,712,288 Total Patients Enrolled

Media Library

CVS Clinical Trial Eligibility Overview. Trial Name: NCT04279483 — N/A
Tobacco Smoking Research Study Groups: CVS Group, 7-11 Group, Control
Tobacco Smoking Clinical Trial 2023: CVS Highlights & Side Effects. Trial Name: NCT04279483 — N/A
CVS 2023 Treatment Timeline for Medical Study. Trial Name: NCT04279483 — N/A
Tobacco Smoking Patient Testimony for trial: Trial Name: NCT04279483 — N/A
~53 spots leftby Oct 2025