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STP705 for Abdominal Obesity

Phase 1
Waitlist Available
Led By Mark Nestor, MD
Research Sponsored by Sirnaomics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 weeks
Awards & highlights

Summary

This trial is testing how well different doses of a new medication work, compared to a fake medication (vehicle), in people who do not know if they are taking the real medication or the fake one.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Incidence (severity and causality) of any AEs
Number of subjects with presence and severity of the following Local Skin Reactions (LSR): erythema, edema, bruising.
Number of subjects with presence and severity of the following Local Skin Reactions (LSR): pain and stinging/burning.

Trial Design

7Treatment groups
Experimental Treatment
Placebo Group
Group I: STP705, 320ug/mL, 1.0 ccExperimental Treatment1 Intervention
Volume of Injection 1.0cc
Group II: STP705, 320ug/mL, 0.5 ccExperimental Treatment1 Intervention
Volume of Injection 0.5cc
Group III: STP705, 240ug/mL, 1.0 ccExperimental Treatment1 Intervention
Volume of Injection 1.0cc
Group IV: STP705, 240 ug/mL, 0.5 ccExperimental Treatment1 Intervention
Volume of Injection 0.5cc
Group V: STP705, 120ug/mL, 1.0 ccExperimental Treatment1 Intervention
Volume of Injection 1.0cc
Group VI: STP705, 120ug/mL, 0.5 ccExperimental Treatment1 Intervention
Volume of Injection 0.5cc
Group VII: VehiclePlacebo Group1 Intervention
1.0cc placebo
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
STP705
2022
Completed Phase 2
~180

Find a Location

Who is running the clinical trial?

SirnaomicsLead Sponsor
11 Previous Clinical Trials
329 Total Patients Enrolled
Mark Nestor, MDPrincipal InvestigatorCenter for Clinical and Cosmetic Research
3 Previous Clinical Trials
82 Total Patients Enrolled
~3 spots leftby Jul 2025