Angiogram for Head and Neck Cancer

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Fred Hutch/University of Washington Cancer Consortium, Seattle, WAHead and Neck Cancer+1 MoreAngiogram - Procedure
Eligibility
18 - 80
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test whether embolization done prior to surgery will improve surgical outcomes in head and neck tumors with large amounts of blood vessels.

Eligible Conditions
  • Head and Neck Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 4 Secondary · Reporting Duration: Intraoperatively

Hour 24
Adverse events (AE) related to angiography or embolization
Directly after the embolization
Success of embolization
Intraoperatively
Intraoperative blood loss
Hour 48
Perioperative blood transfusion volume
Time (minutes) from skin incision to skin closure
Surgical procedure time

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Treatment (PVA, EOV, tumor vessel embolization)
1 of 1

Experimental Treatment

20 Total Participants · 1 Treatment Group

Primary Treatment: Angiogram · No Placebo Group · Phase 1

Treatment (PVA, EOV, tumor vessel embolization)Experimental Group · 7 Interventions: Iodixanol, Ethiodized Oil, Arterial Embolization, Computed Tomography, Angiogram, Polyvinyl Alcohol, Chart Abstraction · Intervention Types: Other, Drug, Procedure, Procedure, Procedure, Drug, Other
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Arterial Embolization
2016
Completed Phase 2
~10
Computed Tomography
2017
Completed Phase 2
~3410

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: intraoperatively

Who is running the clinical trial?

University of WashingtonLead Sponsor
1,609 Previous Clinical Trials
1,572,850 Total Patients Enrolled
GuerbetIndustry Sponsor
62 Previous Clinical Trials
93,046 Total Patients Enrolled
Melanie WalkerPrincipal InvestigatorFred Hutch/University of Washington Cancer Consortium
Do LimStudy DirectorFred Hutch/University of Washington Cancer Consortium

Eligibility Criteria

Age 18 - 80 · All Participants · 13 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
The study is open to people at all stages of the medical condition being studied.
You can participate if you have received treatments for your condition in the past.
You have a tumor in your head or neck that is larger than 2 cm and has spread beyond its original site.
You are expected to live for at least three more months.

Frequently Asked Questions

What are the requirements to take part in this research experiment?

"This clinical trial seeks 20 participants with malignant neoplasms aged between 18 and 80. To be eligible, they must have a blood supply from the external carotid artery, intend to undertake surgical resection of their tumors, meet imaging requirements through MRI or CT scans, may have prior therapies under their belt; adults within the specified age range are also required with a minimum life expectancy period of 3 months. Moreover, applicants need an eGFR above 30 mL/min/1.73 m^2 not being pregnant at angiographic intervention and having extra-axial head & neck tumours greater than 2 cm in size." - Anonymous Online Contributor

Unverified Answer

Does this medical trial admit seniors over the age of 65?

"This trial only allows people aged 18 to 80, with 315 studies catering towards minors and 2,553 targeting patients over the age of 65." - Anonymous Online Contributor

Unverified Answer

What is the maximum capacity of participants enrolled in this research?

"Affirmative. The information listed on clinicaltrials.gov discloses that this research is actively searching for participants who meet the eligibility criteria. This trial was initially posted in December 1, 2022 and recently updated in November 4, 2022; a total of 20 patients are needed from one medical center to participate." - Anonymous Online Contributor

Unverified Answer

Is this clinical trial open to new participants at the moment?

"Affirmative. Clinicaltrials.gov's records demonstrate that this clinical trial, which was initially made available on December 1st 2022, is currently recruiting participants. The study requires 20 patients to be recruited from only one medical centre." - Anonymous Online Contributor

Unverified Answer

Has Angiogram been endorsed by the FDA?

"This experimental drug has been assigned a rating of 1, as there is only limited evidence regarding its safety and effectiveness." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.