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Ketorolac for Polytrauma
Study Summary
This trialaims to investigate whether early administration of non-steroidal anti-inflammatory drugs can improve patient outcomes, reduce opioid use, and improve patient pain after hospital discharge. It may provide new insights into the opioid epidemic and alternative pain management strategies.
- Polytrauma
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have AIDS.You currently have a bleeding ulcer or other active gastrointestinal bleeding.You have been taking steroids or drugs that affect your immune system for a long time or have had an organ transplant in the past.You are currently taking pain medication that contains opioids or receiving treatment for opioid addiction.You are pregnant.You have a chronic condition that affects your kidneys, liver, or lungs.You have a pre-existing medical condition that causes inflammation, such as inflammatory arthritis or inflammatory bowel disease.You are allergic to non-steroidal anti-inflammatory drugs (NSAIDs).You have had a heart attack before.You have long-term heart disease.You are at risk of severe bleeding or have experienced severe bleeding in the past.
- Group 1: Standard of Care without NSAID
- Group 2: Standard of Care with NSAID
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Have prior experiments demonstrated the benefits of Ketorolac?
"Presently, 38 clinical trials involving Ketorolac are being conducted across 57 sites. 8 of these studies have progressed to Phase 3 with the majority located in Los Angeles, California."
How many test subjects are participating in this experiment?
"At present, this study is not enrolling participants. It was initially posted on February 28th 2019 and was last edited November 4th 2022. For those interested in other trials, there are 7 polytrauma studies recruiting patients and 38 ketorolac clinical trials admitting individuals."
Has Ketorolac been granted the stamp of approval by the FDA?
"The limited data backing Ketorolac's efficacy and safety led our team at Power to rate its safety a 1 on the scale of 1-3."
To which maladies is Ketorolac commonly prescribed?
"Ketorolac is a popular treatment for ocular itching, as well as pain relief, the induction of nerve blocks, and pupil dilation."
Could I participate in this experiment?
"For inclusion into this clinical trial, individuals must have suffered polytrauma and be between 18-65 years of age. Approximately 69 total patients are eligible to participate."
Are there still opportunities to enroll in this research initiative?
"Per the details available on clinicaltrials.gov, this medical study is not taking in new patients at present time. Originally posted on February 28th 2019 and last modified November 4th 2022, it appears that recruitment has closed for now; however there are 45 other trials seeking patient enrolment currently."
Is eligibility for this trial limited to those above a certain age, such as 40?
"This medical study is open to those aged 18 years and older, up to 65."
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