← Back to Search

Platelet Rich Plasma for Infertility

Q: Is participation in this medical study open to the public?

For consideration, those with <a href="https://www.withpower.com/clinical-trials/infertility">infertility</a> between 18 and 45 years of age must apply. Approximately 40 participants are required for the trial to meet its objectives.

Q: Is enrollment open to those aged seventy-five and above in this research?

To be accepted into the trial, applicants must be between 18 to 45 years old. Additionally, there are 14 trials for those who have not yet reached legal age and 33 clinical studies available for patients aged 65 or over.

Q: Are there currently any opportunities to join this medical trial?

Affirmative. Details found on clinicaltrials.gov verify that the experiment described is presently recruiting participants, beginning with its initial post of 16th January 2019 and most recently edited 15th December 2021. The trial hopes to acquire 40 patients from a single research centre.

Q: How many participants are eligible for this research study?

Affirmative. According to the clinicaltrials.gov platform, this research program is presently looking for 40 patients from a single site and was initially posted on January 16th 2019 with its latest update being December 15th 2021.

Phase < 1

Waitlist Available

Led By Lusine Aghajanova, M.D.

Research Sponsored by Stanford University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 10 months following transfer

Awards & highlights

Study Summary

This trial will test whether a person's own blood can help them overcome difficulties conceiving.

Who is the study for?

This trial is for women aged 18-45 who have had at least three unsuccessful embryo transfers or two failed transfers of embryos with normal chromosomes. Participants must have a healthy uterine cavity and be planning in vitro fertilization at Stanford Fertility and Reproductive Health using either a genetically tested embryo, a high-quality blastocyst if under 37, or an egg donor's blastocyst.Check my eligibility

What is being tested?

The study is testing the effectiveness of Platelet Rich Plasma (PRP) versus a placebo in improving pregnancy rates for women with recurrent implantation failure. It's a randomized controlled pilot study where participants will receive either PRP or an inactive substance without knowing which one they're getting.See study design

What are the potential side effects?

While specific side effects are not detailed here, PRP involves using the patient’s own platelets to stimulate healing and regeneration, which generally has minimal risks. Possible side effects may include irritation or pain at the injection site.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 10 months following transfer

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~10 months following transfer

This trial's timeline: 3 weeks for screening, Varies for treatment, and 10 months following transfer for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Live birth rate

Secondary outcome measures

Pregnancy

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: PRPExperimental Treatment1 Intervention

Patient with recurrent implantation failure who receives intrauterine infusion of platelet rich plasma

Group II: PlaceboPlacebo Group1 Intervention

Patient with recurrent implantation failure who receives intrauterine infusion of embryo culture media

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Platelet rich plasma

2010

Completed Phase 4

~1300

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Stanford UniversityLead Sponsor

2,394 Previous Clinical Trials

17,341,570 Total Patients Enrolled

12 Trials studying Infertility

2,345 Patients Enrolled for Infertility

Lusine Aghajanova, M.D.2.01 ReviewsPrincipal Investigator - Stanford University

Stanford University

2Patient Review

Dr. Aghajanova and her team made several mistakes during my IUI cycles, so I had to change clinics.

Media Library

Placebo Clinical Trial Eligibility Overview. Trial Name: NCT03379649 — Phase < 1

Infertility Research Study Groups: PRP, Placebo

Infertility Clinical Trial 2023: Placebo Highlights & Side Effects. Trial Name: NCT03379649 — Phase < 1

Placebo 2023 Treatment Timeline for Medical Study. Trial Name: NCT03379649 — Phase < 1

Infertility Patient Testimony for trial: Trial Name: NCT03379649 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is participation in this medical study open to the public?

"For consideration, those with infertility between 18 and 45 years of age must apply. Approximately 40 participants are required for the trial to meet its objectives."

Answered by AI

Is enrollment open to those aged seventy-five and above in this research?

"To be accepted into the trial, applicants must be between 18 to 45 years old. Additionally, there are 14 trials for those who have not yet reached legal age and 33 clinical studies available for patients aged 65 or over."

Answered by AI

Are there currently any opportunities to join this medical trial?

"Affirmative. Details found on clinicaltrials.gov verify that the experiment described is presently recruiting participants, beginning with its initial post of 16th January 2019 and most recently edited 15th December 2021. The trial hopes to acquire 40 patients from a single research centre."

Answered by AI

How many participants are eligible for this research study?

"Affirmative. According to the clinicaltrials.gov platform, this research program is presently looking for 40 patients from a single site and was initially posted on January 16th 2019 with its latest update being December 15th 2021."

Answered by AI

Who else is applying?

What state do they live in?

Louisiana

Georgia

Nevada

How old are they?

18 - 65

What site did they apply to?

Stanford Fertility and Reproductive Health

What portion of applicants met pre-screening criteria?

Did not meet criteria

Met criteria

How many prior treatments have patients received?

Why did patients apply to this trial?

My Name is Lenette Howell and I am 45 years old and will be 46 in July. I have a bachelors and masters in Social work and a second masters in Special Educaiton. I am currently an crisis response Social Worker . My previous employment was a elementary special education teacher. I was a teacher for 8 years and I enjoyed every bit of it. Preciously I was a foster care social worker with the state of Georgia. All of my careers involve children as I have always loved working with kids. I have spent my adult life working with kids and have always longed for one of my own. I started my trying to conceive journey back in 2009 when I experience a miscarriage at 10 weeks. It was soon discovered that I had fibroids. I was told at that time that if they did not bother me then it wouldn’t be an issue. I never got pregnant after that. I had my first myomectomy in 2015 in which they removed 28 large fibroids. I was then put on clomid for about 6 cycles with, however, I still did not get pregnant. I then went to Shady grove to get testing done to see what was the issue and was diagnosed with unexplained infertility with low egg reserve. I tried for 3 years with Shady Grove and I have done 2 cycles of IUI with no live pregnancy.

PatientReceived no prior treatments

Recent research and studies

Human FertilityJournal

The Effects of Autologous Platelet-rich Plasma in Repeated Implantation Failure: A Randomized Controlled Trial

Nazari, Leila, Saghar Salehpour, Maryam Sadat Hosseini, and Parisa Hashemi Moghanjoughi. 2019. “The Effects of Autologous Platelet-rich Plasma in Repeated Implantation Failure: A Randomized Controlled Trial”. Human Fertility. Informa UK Limited. doi:10.1080/14647273.2019.1569268.

clinicaltrials.govStudy

Platelet Rich Plasma for Patients With Recurrent Implantation Failure

Lusine Aghajanova 2019. "Platelet Rich Plasma for Patients With Recurrent Implantation Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03379649.