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Phase II: Lifestyle treatment for Obesity

N/A

Waitlist Available

Led By Elizabeth Parks, PhD

Research Sponsored by University of Missouri-Columbia

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 day

Awards & highlights

Study Summary

This trial will examine if there is a relationship between the amount of fat stored in the liver and the liver's ability to metabolize fat.

Eligible Conditions

Obesity
Non-alcoholic Fatty Liver Disease

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 day

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 day

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Liver mitochondrial gene expression

Secondary outcome measures

Histology to determine the amount of fibrosis in the liver

Liver mitochondrial fat oxidation

Trial Design

3Treatment groups

Experimental Treatment

Placebo Group

Group I: Phase II: Lifestyle treatmentExperimental Treatment1 Intervention

Subjects will undergo lifestyle modification to cause weight loss and improved fitness

Group II: Phase I: Observational studiesExperimental Treatment1 Intervention

Patients are eligible who are undergoing either bariatric surgery or a liver biopsy for the diagnosis of nonalcoholic fatty liver disease

Group III: Phase II: Control treatmentPlacebo Group1 Intervention

Subjects will be given dietary advice and a stretching program.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Phase II: Lifestyle treatment

2017

N/A

~340

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of Missouri-ColumbiaLead Sponsor

361 Previous Clinical Trials

627,658 Total Patients Enrolled

20 Trials studying Obesity

1,866 Patients Enrolled for Obesity

Elizabeth Parks, PhD4.58 ReviewsPrincipal Investigator - University of Missouri-Columbia

University of Missouri-Columbia

1 Previous Clinical Trials

5Patient Review

I found Elizabeth to be both caring and professional. I would wholeheartedly recommend her to others seeking out a PA.

Jamal Ibdah, MDPrincipal InvestigatorUniversity of Missouri-Columbia

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many individuals have been accepted into this clinical experiment?

"Indeed. According to publically available information on clinicaltrials.gov, this trial is currently accepting new participants; it was initially posted in August of 2017 and amended as recently as October 2021. A total of 90 patients will be recruited at one location for the study."

Answered by AI

Is this opportunity available to volunteers at the moment?

"Affirmative. Clinicaltrials.gov states that this medical research project is currently seeking participants, having been initially posted on August 9th 2017 and last updated October 22nd 2021. A total of 90 patients must be recruited from a single clinical trial site."

Answered by AI

Are participants aged 25 and older eligible for this research study?

"The age range for this trial is 22 to 65. There are 218 trials that cater specifically to younger individuals and 773 studies designed with the elderly in mind."

Answered by AI

Could I register for participation in this experiment?

"To qualify for this study, applicants must be 22 to 65 years old and have a BMI that falls into the obesity category. Up to 90 participants can join this clinical trial."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

The Liver Health Study for Patients With NAFLD

Elizabeth Parks 2017. "The Liver Health Study for Patients With NAFLD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03151798.