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[14C]-benzo[a]pyrene for Environmental Exposures
Study Summary
This trial is evaluating how the body processes a small amount of a chemical called benzo[a]pyrene, given four times at different doses.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have been exposed to certain chemicals (found in jobs like roofing, paving, and firefighting) that can increase the risk of developing a certain type of lung disease.You have a history of stomach or intestinal surgery, or you have certain digestive disorders like Crohn's disease, celiac disease, IBS, or colitis.You take medications that can affect how your stomach and intestines work or how your body absorbs nutrients.You currently have or have had kidney or liver problems in the past.
- Group 1: 100 ng dose
- Group 2: 25 ng dose
- Group 3: 250 ng dose
- Group 4: 50 ng dose
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is enrollment available for individuals who are of age twenty or over in this trial?
"The parameters for inclusion in this study necessitate that all participants are between 21 and 65 years old. There exists 6 trials specifically designed for those beneath the age of majority, as well 12 research studies focused on individuals above retirement age."
Is this research endeavor actively recruiting participants?
"Unfortunately, according to clinicaltrials.gov this investigation is no longer recruiting patients after being initially posted on April 17th 2018 and last updated on October 17 2022. Fortunately though, there are presently 15 other medical studies actively seeking participants."
Am I eligible to participate in this clinical research?
"This clinical trial seeks 8 volunteers between the ages of 21 and 65 who have experienced environmental exposures. To be considered, participants must meet additional requirements such as being post-menopausal or having undergone a surgical sterilization procedure. Other dietary restrictions include avoiding cruciferous vegetables, I3C or DIM supplements, smoked or cured meats/cheeses, and charcoal-grilled foods for two weeks prior to and during each study cycle (gas grilled food is permissible). Additionally, those enrolled in this medical research must refrain from donating blood one month before starting their involvement with the study activities until one month after it concludes."
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