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Behavioural Intervention

Approach Bias Training for Nicotine Addiction

Led By Lorra Garey, Ph.D
Research Sponsored by University of Houston
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Screening 3 weeks
Treatment Varies
Follow Up week 1-7, 9, and 11 of participation
Awards & highlights


This trial will evaluate the effectiveness of a retraining program to help people quit smoking cigarettes and using electronic cigarettes. The study will follow 90 experienced users who are motivated to quit as they try to quit on their own.

Who is the study for?
This trial is for adults who've used both regular cigarettes and e-cigarettes with nicotine almost every day over the last month, can read and speak English fluently, want to quit nicotine (scoring at least 5 out of 10 in motivation), and own an Android smartphone. It's not for those currently getting treatment for mental illness or addiction, using other quitting aids like nicotine patches or certain medications, or unable to consent.Check my eligibility
What is being tested?
The study tests a 'bias training' method to help people quit smoking by comparing three groups: one uses bias training for both cigarettes and e-cigs (CC+ECIG Condition), another only for cigarettes (CC Condition), while the third group gets a fake intervention (Sham Condition). Participants are randomly assigned to these groups during their self-guided attempt to stop using nicotine.See study design
What are the potential side effects?
Since this trial involves behavioral interventions rather than medication, traditional side effects are not expected. However, participants may experience frustration or stress due to quitting attempts or possible cravings triggered during approach bias retraining exercises.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 1-7, 9, and 11 of participation
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 1-7, 9, and 11 of participation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Approach Bias
Biochemically-Verified Point Prevalence Abstinence
+4 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: CC+ECIG ConditionExperimental Treatment1 Intervention
Combustible Cigarette (CC) and Electronic Cigarette (ECIG) users will be trained to avoid CC and ECIG-related images and approach positive images.
Group II: CC Only ConditionActive Control1 Intervention
Participants in this arm will be trained to avoid only combustible cigarette images, not electronic cigarettes images.
Group III: Sham ConditionPlacebo Group1 Intervention
Participants will pull and push all pictures of CC and ECIG images equally with no preference towards one or the other.

Find a Location

Who is running the clinical trial?

University of HoustonLead Sponsor
148 Previous Clinical Trials
47,508 Total Patients Enrolled
Lorra Garey, Ph.DPrincipal InvestigatorAssistant Research Professor
~8 spots leftby Sep 2024