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Imaging & Biomarker Analysis for Stroke Recovery (MORSE Trial)
N/A
Waitlist Available
Led By Malgorzata Miller, MD
Research Sponsored by Spectrum Health Hospitals
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Imaging confirmed ischemic stroke within 7 days of stroke onset
Age > 18 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights
MORSE Trial Summary
This trialseeks to use imaging & molecular biomarkers to better understand stroke recovery in humans, in order to reduce disabilities & deficits.
Who is the study for?
The MORSE study is for adults over 18 who've had an imaging-confirmed ischemic stroke within the past week. Participants should have slight arm weakness or better, and be relatively independent in daily activities before their stroke. People with active cancer, severe anemia, sepsis, or suspected heart infection cannot join.Check my eligibility
What is being tested?
This trial aims to understand stroke recovery by using DTI (a type of MRI scan) images and analyzing blood plasma biomarkers. The goal is to integrate these methods as diagnostic tools to observe brain repair mechanisms after a stroke.See study design
What are the potential side effects?
Since this study involves non-invasive imaging and blood tests rather than drug treatments, side effects are minimal but may include discomfort from lying still during scans and potential bruising from blood draws.
MORSE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I had a stroke confirmed by imaging within the last week.
Select...
I am older than 18 years.
Select...
I have some weakness in my arm or hand.
MORSE Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Establish plasma metabolite biomarkers that mirror neuronal repair and identify structural changes following ischemic strokes
Secondary outcome measures
Change in Fugl-Meyer
MORSE Trial Design
1Treatment groups
Experimental Treatment
Group I: DTI Outcomes and BiomarkersExperimental Treatment1 Intervention
Imaging and Lab Collection
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Who is running the clinical trial?
Spectrum Health HospitalsLead Sponsor
64 Previous Clinical Trials
553,188 Total Patients Enrolled
1 Trials studying Stroke
682 Patients Enrolled for Stroke
Georgetown UniversityOTHER
343 Previous Clinical Trials
136,481 Total Patients Enrolled
8 Trials studying Stroke
3,028 Patients Enrolled for Stroke
Malgorzata Miller, MDPrincipal InvestigatorSpectrum Health Hospital
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I currently have sepsis.I have some weakness in my arm or hand.I am older than 18 years.My cancer is active and not in remission.Your red blood cell count is very low.I am suspected to have a bacterial infection in my heart.I had a stroke confirmed by imaging within the last week.Your physical ability before the stroke was not severely limited.
Research Study Groups:
This trial has the following groups:- Group 1: DTI Outcomes and Biomarkers
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there any current openings for participation in this experiment?
"Investigating clinicaltrials.gov reveals that this medical investigation is no longer recruiting participants at present, as it was first posted on October 1st 2018 and last edited November 22nd 2022. Despite this, there are still 1044 other trials actively searching for individuals to join their research programs."
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