High-Intensity Stepping Training for Stroke Recovery
(LRC Trial)
Trial Summary
What is the purpose of this trial?
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment High-Intensity Stepping Training for Stroke Recovery?
Is high-intensity exercise safe for stroke recovery?
How does high-intensity stepping training differ from other stroke recovery treatments?
High-intensity stepping training is unique because it focuses on task-specific stepping at higher cardiovascular intensities, which significantly improves walking and balance outcomes compared to usual care. This approach emphasizes a higher dose and intensity of exercise, leading to better recovery of locomotor function post-stroke.12359
Research Team
Thomas G Hornby
Principal Investigator
Indiana University School of Medicine
Eligibility Criteria
The LRC trial is for individuals who have had their first stroke and are currently in inpatient rehabilitation. They must be able to understand simple commands, provide consent, and get medical clearance from a rehab doctor. Participants should have one-sided weakness (hemiparesis) and be within 15-30 days post-stroke.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Observational Evaluations
Participants undergo observational evaluations to assess neurological and locomotor recovery
High-Intensity Training (HIT)
Participants receive high-intensity training to improve locomotor function
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- High-Intensity Training
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana University
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
Rehabilitation Hospital of Indiana
Collaborator