Perturbation Training for Stroke
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to assist individuals who have had a stroke and are at risk of falling, significantly affecting their daily lives. It tests two methods to improve balance while walking: responding to sudden changes (Reactive Perturbations) and anticipating them (Proactive Perturbations). The trial seeks participants who had a stroke over six months ago, have fallen or fear falling, and can walk on a treadmill without support. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that could enhance balance and reduce fall risk for stroke survivors.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that these perturbation methods are safe for improving post-stroke walking balance?
Research has shown that perturbation-based balance training (PBT) can help stroke patients improve their balance and ability to walk. This training involves controlled movements that challenge balance, potentially preventing falls. Some studies found that PBT reduced fall rates in daily life by up to 52%. However, the quality of the evidence is often low, so more research is needed to confirm these findings.
Both proactive and reactive techniques in PBT offer similar benefits, improving balance and walking, especially for those with severe balance issues. While the evidence is promising, not all studies have shown strong proof that these methods reduce falls. The training is generally well-tolerated, with no major safety concerns reported.
In summary, both proactive and reactive PBT techniques appear safe for stroke patients and may help reduce falls and improve balance.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores a novel approach to stroke rehabilitation through perturbation training. Unlike traditional therapies that primarily focus on restoring movement through repetitive exercises, this trial involves two innovative methods: Proactive and Reactive Perturbations. These techniques are designed to challenge and improve balance and coordination by simulating real-life disruptions, potentially leading to quicker and more effective recovery. By targeting the body's ability to adapt to unexpected changes, this approach could offer a significant advantage over standard physical therapy, potentially speeding up recovery times and improving overall outcomes for stroke patients.
What evidence suggests that these perturbation methods could be effective for improving post-stroke walking balance?
Research shows that a type of balance training called perturbation training may help improve balance in people who have had a stroke. In this trial, participants will be assigned to either proactive or reactive perturbation training. Studies have found that proactive perturbation training can greatly improve balance and walking ability, especially for those with serious balance problems. However, it doesn't significantly boost confidence in balancing, and the quality of the evidence is low. Participants in the reactive perturbations arm have shown improved control over quick steps needed to prevent falls. More reactive exercises are linked to better balance recovery. Overall, both training methods seem promising for improving balance after a stroke, but more research is needed to confirm their effectiveness in everyday life.12678
Who Is on the Research Team?
Jesse Dean
Principal Investigator
Medical University of South Carolina
Are You a Good Fit for This Trial?
This trial is for individuals who had a stroke at least 6 months ago, have experienced falls or fear falling, can walk on a treadmill without support, and have a walking speed of at least 0.2 meters per second. It's not suitable for those with certain heart conditions, other neurological disorders or dementia, severe lower limb orthopedic issues, cerebellar damage, extremely high blood pressure, significant visual impairments, recent DVT/pulmonary embolism events or uncontrolled diabetes.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo perturbation training to improve post-stroke walking balance and reduce fall incidence
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Proactive Perturbations
- Reactive Perturbations
Find a Clinic Near You
Who Is Running the Clinical Trial?
Medical University of South Carolina
Lead Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborator