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Perturbation Training for Stroke

N/A

Recruiting

Led By Jesse Dean

Research Sponsored by Medical University of South Carolina

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Gait speed of at least 0.2 m/s

Ability to walk on a treadmill without a cane or walker

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 32 weeks (12-week period pre-intervention; 12-week period post-intervention)

Awards & highlights

Study Summary

This trial investigates whether two methods of delivering mechanical perturbations during walking can improve post-stroke walking balance and reduce real-world fall incidence for stroke patients.

Who is the study for?

This trial is for individuals who had a stroke at least 6 months ago, have experienced falls or fear falling, can walk on a treadmill without support, and have a walking speed of at least 0.2 meters per second. It's not suitable for those with certain heart conditions, other neurological disorders or dementia, severe lower limb orthopedic issues, cerebellar damage, extremely high blood pressure, significant visual impairments, recent DVT/pulmonary embolism events or uncontrolled diabetes.Check my eligibility

What is being tested?

The study examines two types of mechanical perturbations during walking—proactive and reactive—to see if they improve balance and reduce the risk of falls in post-stroke patients. Participants will be subjected to these perturbations while walking to assess their effectiveness in enhancing stability.See study design

What are the potential side effects?

While specific side effects are not listed for this type of physical intervention trial, participants may experience discomfort or muscle soreness due to the unusual walking challenges presented by the perturbations.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I can walk at a speed of at least 0.2 meters per second.

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I can walk on a treadmill without needing a cane or walker.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 32 weeks (12-week period pre-intervention; 12-week period post-intervention)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~32 weeks (12-week period pre-intervention; 12-week period post-intervention)

This trial's timeline: 3 weeks for screening, Varies for treatment, and 32 weeks (12-week period pre-intervention; 12-week period post-intervention) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Fall incidence

Secondary outcome measures

Activities-specific Balance Confidence scale

Angular momentum modulation (trained perturbations) Largest rejected perturbation (trunk)

Angular momentum modulation (untrained perturbations) Largest rejected perturbation (trunk)

+11 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Reactive PerturbationsExperimental Treatment1 Intervention

Group II: Proactive PerturbationsExperimental Treatment1 Intervention

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Medical University of South CarolinaLead Sponsor

933 Previous Clinical Trials

7,394,549 Total Patients Enrolled

67 Trials studying Stroke

59,965 Patients Enrolled for Stroke

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH

1,965 Previous Clinical Trials

2,672,711 Total Patients Enrolled

79 Trials studying Stroke

5,301 Patients Enrolled for Stroke

Jesse DeanPrincipal InvestigatorMedical University of South Carolina

Media Library

Proactive Perturbations 2023 Treatment Timeline for Medical Study. Trial Name: NCT04855032 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this clinical experiment accepting participants at present?

"Yes, according to the clinicaltrials.gov website, this study is currently in need of participants. It was originally posted on October 6th 2021 and has since been updated as recently as March 10th 2022. The investigation requires 86 volunteers from a single centre."

Answered by AI

How many participants are involved in this experiment?

"Affirmative. The clinicaltrials.gov website states that this medical trial is currently accepting applicants, which began on October 6th 2021 and was last updated on March 10th 2022. Researchers are aiming to recruit 86 people from a single site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Post-stroke Perturbation Training

Jesse Dean 2021. "Post-stroke Perturbation Training". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04855032.