Radiation Therapy for Prostate Cancer
(FORT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The study is a randomized study that compares 5 radiation therapy treatments to 2 radiation therapy treatments in men with low or intermediate-risk prostate cancer.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is radiation therapy generally safe for prostate cancer treatment?
Research shows that advanced radiation therapy techniques like intensity-modulated radiotherapy (IMRT) and image-guided radiotherapy (IGRT) are generally safe, with some patients experiencing mild to moderate side effects such as gastrointestinal (GI) and genitourinary (GU) issues. The use of these techniques can reduce the risk of side effects compared to older methods.12345
How is radiation therapy unique for treating prostate cancer?
Radiation therapy for prostate cancer, especially with advanced techniques like intensity-modulated radiation therapy (IMRT) and image-guided radiotherapy (IGRT), allows for higher doses of radiation to be delivered more precisely to the tumor, reducing damage to surrounding healthy tissue and potentially improving treatment outcomes compared to older methods.678910
What data supports the effectiveness of this treatment for prostate cancer?
Radiation therapy is a valid alternative to surgery for prostate cancer, with dose-escalated radiation improving patient outcomes. Techniques like intensity-modulated radiation therapy (IMRT) and stereotactic body radiotherapy (SBRT) have shown promise in improving local control and reducing side effects.611121314
Who Is on the Research Team?
Emily Weg, M.D.
Principal Investigator
Weill Medical College of Cornell University
Are You a Good Fit for This Trial?
This trial is for men over 18 with low or intermediate-risk prostate cancer, who are generally healthy and can undergo MRI-guided radiotherapy. They should not have had pelvic radiation before, no large prostate on MRI (>80 cc), no recent TURP surgery, no metastatic disease, and no history of inflammatory bowel disease or hip replacements.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either 5 or 2 MRI-guided adaptive radiotherapy treatments for prostate cancer
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments at multiple intervals
What Are the Treatments Tested in This Trial?
Interventions
- Radiation Therapy
Radiation Therapy is already approved in European Union, United States, Canada, Japan, China, Switzerland for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor
Progenics Pharmaceuticals, Inc.
Industry Sponsor
Viewray Inc.
Industry Sponsor