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Exercise Intensity for Stroke Rehabilitation
N/A
Recruiting
Led By Marc Roig, PhD
Research Sponsored by McGill University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights
Study Summary
This trial will compare the effects of high-intensity interval training (HIIT) vs. moderate-intensity continuous training (MICT) on brain plasticity, cardiovascular health, and psychosocial predictors of physical activity.
Who is the study for?
This trial is for individuals who had their first stroke 6-60 months ago, can walk at least 10 meters (with or without help), and have a basic ability to follow instructions. It's not suitable for those with other serious health issues that make exercise unsafe, currently in another rehab program, or have pain worsened by exercise.Check my eligibility
What is being tested?
The study compares two types of exercises over 12 weeks: Moderate-Intensity Continuous Training (MICT) and High-intensity Interval Training (HIIT). Both are done on a machine that works arms and legs. Researchers will check how these affect brain recovery, heart health, mood, motivation, and walking.See study design
What are the potential side effects?
While the document doesn't list specific side effects, typical risks from moderate to high-intensity exercise may include muscle soreness, fatigue, shortness of breath during activity. The eligibility criteria suggest avoiding participants where exercise could lead to significant discomfort or risk.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 12 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Cortico-spinal excitability
Secondary outcome measures
Arterial stiffness
Cardiorespiratory fitness
Diastolic resting blood pressure
+4 moreOther outcome measures
Enjoyment
Gait speed
Motivation
+2 moreTrial Design
2Treatment groups
Experimental Treatment
Group I: Moderate-intensity continuous trainingExperimental Treatment1 Intervention
Intensity will be determined using a combination of heart rate reserve (HRR, calculated as HRR= [max HR - resting HR] x [% training] + [resting HR]) and ratings of perceived exertion (RPE). The MICT protocol will be increased using a progression schedule previously used (initial intensity at 40% HRR (RPE=9-11), and progressed by 10% HRR every 4 weeks up to 60% HRR (RPE=13-14) will be maintained until the end of the intervention). A 3-minute warm-up and 2-minute cool-down will be performed at 30% HRR (RPE=9-11). The total duration of MICT, including warm-up and cool-down, will be 35 minutes.
Group II: High-intensity interval trainingExperimental Treatment1 Intervention
Intensity will be determined using a combination of heart rate reserve (HRR, calculated as HRR= [max HR - resting HR] x [% training] + [resting HR]) and ratings of perceived exertion (RPE). The protocol will involve 10 60-second intervals of high intensity interspersed with 9 60-second low-intensity intervals. The initial high intensity intervals will start at 80% of the HRR (RPE=14-17) and progress by 10% every 4 weeks. Low intensity intervals will be performed at 30% of HRR (RPE=9-11). Three-minute warm-up and 2-minute cool-down periods will be performed at 30% of HRR. Total HIIT time including warm-up and cool-down is 24 minutes.
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Who is running the clinical trial?
McMaster UniversityOTHER
884 Previous Clinical Trials
2,598,236 Total Patients Enrolled
21 Trials studying Stroke
41,657 Patients Enrolled for Stroke
Jewish Rehabilitation HospitalOTHER
5 Previous Clinical Trials
700 Total Patients Enrolled
2 Trials studying Stroke
130 Patients Enrolled for Stroke
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,345 Previous Clinical Trials
26,453,487 Total Patients Enrolled
37 Trials studying Stroke
651,764 Patients Enrolled for Stroke
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have had a stroke not caused by heart issues or due to a tumor.I have a condition that stops me from being able to exercise.My pain gets worse when I exercise.I am currently participating in a stroke rehabilitation or structured exercise program.It's been 6 to 60 months since my first stroke, confirmed by an MRI or CT scan.I have little to no disability from my condition.My heart health is classified as high risk by the American Heart Association.You have reasons that make it unsafe for you to have transcranial magnetic stimulation.You have trouble thinking, talking, or behaving in a way that could make exercising unsafe for you.You need to have a Montreal Cognitive Assessment score of more than 20, which means you can understand and follow exercise instructions.I can walk at least 10 meters on my own, even with a walking aid.
Research Study Groups:
This trial has the following groups:- Group 1: High-intensity interval training
- Group 2: Moderate-intensity continuous training
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Can I become involved in this experiment?
"In order to qualify for this trial, applicants must have suffered a stroke and be within the age bracket of 40-80. The research team is currently in search of 80 participants."
Answered by AI
Does this research initiative consider senior participants?
"This research project is limited to patients aged 40-80; however, there are 37 studies for minors and 1007 trials available for seniors."
Answered by AI
How many people have been recruited to participate in this experiment?
"Affirmative. According to the listing on clinicaltrials.gov, this research is currently enrolling patients; with the initial post date of January 1st 2020 and latest update from November 17th 2022. Two clinics are needed for recruiting 80 participants in total."
Answered by AI
Are there any vacancies still available for potential participants in this research project?
"According to clinicaltrials.gov, this research is actively recruiting participants at present time. The trial was inaugurated on January 1st 2020 and the data has been freshly updated as of November 17th 2022."
Answered by AI
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