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Behavioural Intervention

Unilateral strength training for Muscular Atrophy (BUST Trial)

N/A

Waitlist Available

Research Sponsored by University of Kansas

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 9-weeks

Awards & highlights

BUST Trial Summary

This trial will evaluate the effect of exercise on improving muscle size, strength, and function in people who have had an ACL reconstruction. 30-40 participants will do exercises 3x/week for 8 weeks and be tested before and after.

Eligible Conditions

Muscular Atrophy
Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Tear

BUST Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 9-weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~9-weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 9-weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in isometric strength of the quadriceps femoris

Change in muscle cross-sectional area of the quadriceps femoris

Secondary outcome measures

Change in body composition

Change in isometric strength of the hamstrings femoris

Change in jump height of both limbs

+3 more

Other outcome measures

Change in dynamic strength of the quadriceps and hamstrings

BUST Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Unilateral strength trainingExperimental Treatment1 Intervention

Resistance training three times per week for 8-weeks on one leg at a time per exercise.

Group II: Bilateral strength trainingActive Control1 Intervention

Resistance training three times per week for 8-weeks on both legs at a time per exercise.

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Who is running the clinical trial?

University of KansasLead Sponsor

147 Previous Clinical Trials

325,861 Total Patients Enrolled

1 Trials studying Muscular Atrophy

410 Patients Enrolled for Muscular Atrophy

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any eligibility criteria for individuals to join the research project?

"To participate in this trial, potential candidates must have sustained an anterior cruciate ligament injury and be between 18 to 35 years of age. Moreover, the recruitment process is looking for 40 participants."

Answered by AI

Are individuals over 40 years of age being accepted in this experiment?

"The age of admission to this trial is set between 18 and 35. Additionally, there are 107 separate trials available for minors aged under eighteen as well as 116 other studies open to seniors above the age of 65."

Answered by AI

How many individuals are afforded the chance to participate in this experiment?

"Affirmative. Clinicaltrials.gov confirms that this trial, published on August 31st 2023, is currently enrolling participants. The research needs to recruit 40 individuals from one site."

Answered by AI

Are there any unfilled vacancies in this research endeavor?

"Confirmed. The clinical trial is presently enrolling participants, with the initial posting of the study occurring on August 31st 2023 and most recent update taking place September 10th 2023. 40 patients are needed at one location for this medical study."

Answered by AI

What goals are being sought to be achieved in this experiment?

"The principal aim of this supervised, 9-week clinical trial is to evaluate the alteration in muscle cross-sectional area of the quadriceps femoris. Auxiliary outcomes comprise a variation in maximal voluntary isometric contraction (MVIC) peak torque, jump height and vertical jump impulse during countermovement jumps from baseline values."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Bilateral Versus Unilateral Strength Training After ACLR

Christopher Cleary, MS, CPSS, CSCS 2023. "Bilateral Versus Unilateral Strength Training After ACLR". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06032247.